Advanced CT Imaging Techniques for Coronary Heart Disease
Trial Summary
What is the purpose of this trial?
Title: Evaluating New Radiation Techniques for Cardiovascular Imaging Background: - Imaging studies such as computed tomography (CT) scans involve the use of radiation to create the pictures. Heart and blood vessel CT scans can cause high radiation exposure. Different methods of creating CT pictures have been developed to reduce the radiation dose. Researchers want to see how effective these new methods are in producing accurate CT scans. Objectives: - To study new ways of taking pictures of the heart or blood vessels using computed tomography. Eligibility: - Adults at least 18 years of age who will be having imaging studies to help detect heart or blood vessel problems. Design: * Participants will be screened with a physical exam and medical history. Blood samples will be taken to check kidney function. * Participants will have a CT scan of the heart and blood vessels. A contrast agent may be used to improve the quality of the images. The scanning session may last up to 2 hours. * Timing of and the need for follow up contact will depend on results from the initial scan and may be repeated to assess for late events. Telephone, office contact, or other follow-up of subjects may be done after CCTA to evaluate if the subject had subsequent cardiovascular testing. Further follow up will be based on reported test results.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment The Toshiba Aquilion ONE CT system, Toshiba Aquilion ONE CT scanner for coronary heart disease?
Is the Toshiba Aquilion ONE CT scanner safe for use in humans?
How does the treatment in the clinical trial 'Advanced CT Imaging Techniques for Coronary Heart Disease' differ from other treatments for this condition?
This treatment uses advanced CT imaging techniques, such as multislice computed tomography (MSCT) and coronary computed tomography angiography (CCTA), to noninvasively assess coronary heart disease with high accuracy. It offers unique benefits like detailed evaluation of coronary artery stenoses, bypass patency, and myocardial function, while also incorporating dose-reduction strategies to minimize radiation exposure.45101112
Research Team
Marcus Y Chen, M.D.
Principal Investigator
National Heart, Lung, and Blood Institute (NHLBI)
Eligibility Criteria
This trial is for adults over 18 who need a coronary CT angiography exam to check their heart or blood vessels. They must understand and sign consent, be able to follow up, and have working kidneys if using contrast. Pregnant individuals or those with severe kidney issues can't join.Inclusion Criteria
Exclusion Criteria
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
Imaging
Participants will have a CT scan of the heart and blood vessels. A contrast agent may be used to improve the quality of the images.
Follow-up
Timing of and the need for follow-up contact will depend on results from the initial scan and may be repeated to assess for late events. Telephone, office contact, or other follow-up of subjects may be done after CCTA to evaluate if the subject had subsequent cardiovascular testing.
Treatment Details
Interventions
- The Toshiba Aquilion ONE CT system (Radiation)
Find a Clinic Near You
Who Is Running the Clinical Trial?
National Heart, Lung, and Blood Institute (NHLBI)
Lead Sponsor