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Electrolyte Solution

Electrolyte Drinks for Dehydration (LIV-D2O Trial)

N/A
Recruiting
Research Sponsored by Arizona State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 18-60 years
Be between 18 and 65 years old
Must not have
Cardiovascular disease
Bariatric surgery
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at 30 minutes, 1 hour, 2 hours, 3 hours and 4 hours of the rehydration period
Awards & highlights

Summary

This trial aims to test how well a drink containing electrolytes and glucose can help people rehydrate after exercising and losing fluids. Previous research shows that drinks with carbohydrates and electrolytes are better at rehydr

Who is the study for?
This trial is for adults aged 18-60 who exercise at least twice a week and have maintained a stable weight (less than 5 pounds change) over the last two months. It's not suitable for those with night shift work, on thyroid meds, past bariatric surgery, or with heart, kidney, liver diseases. Also excluded are those in another study or weighing over 110 pounds.
What is being tested?
The study tests how well different drinks rehydrate after exercise-induced dehydration: plain water versus Liquid IV Sugar Free and Liquid IV Hydration Multiplier—both containing electrolytes and glucose which may enhance fluid intake and reduce urine output.
What are the potential side effects?
While specific side effects aren't listed for this trial, potential ones from electrolyte-glucose drinks can include nausea, bloating, or an upset stomach due to the ingredients used to improve hydration.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 18 and 60 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I have a heart condition.
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I have had weight loss surgery.
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I weigh more than 110 pounds.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at 30 minutes, 1 hour, 2 hours, 3 hours and 4 hours of the rehydration period
This trial's timeline: 3 weeks for screening, Varies for treatment, and at 30 minutes, 1 hour, 2 hours, 3 hours and 4 hours of the rehydration period for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Cumulative urine output
Net fluid balance
Rate of absorption
+1 more
Secondary study objectives
Free Osmotic Clearance
Free water Clearance
Plasma copeptin
+4 more

Trial Design

3Treatment groups
Experimental Treatment
Placebo Group
Group I: Low Sugar electrolyte solutionExperimental Treatment1 Intervention
10 grams of carbohydrate, 1060 milligrams of sodium, and 760 milligrams of potassium per liter. Sugar free Liquid IV
Group II: Carbohydrate Electrolyte solutionExperimental Treatment1 Intervention
Drink with 22 grams of carbohydrate, 1020 milligrams of sodium, and 760 milligrams of potassium per liter. Hydration multiplier liquid IV
Group III: WaterPlacebo Group1 Intervention
Rehydration with low mineral content bottle water

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Who is running the clinical trial?

Arizona State UniversityLead Sponsor
294 Previous Clinical Trials
107,410 Total Patients Enrolled
8 Trials studying Dehydration
2,233 Patients Enrolled for Dehydration
~9 spots leftby Dec 2024
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