Contingency Management for Depression and Cannabis Use
(CLEAR Trial)
Trial Summary
What is the purpose of this trial?
The goal of this study is to disentangle relationships between acute cannabis use and withdrawal on proximal depression and suicide risk and recovery in adolescents ages 12-18 years by incorporating time-varying patterns of substance use, mood, and SI. This project aims to guide the development of scalable, individualized, accessible, and affordable interventions aimed to reduce depression and suicide risk among adolescents.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators.
What data supports the effectiveness of the treatment Contingency Management for cannabis abstinence?
Research shows that Contingency Management (CM), which uses rewards to encourage positive behavior like staying off cannabis, is effective in helping people reduce cannabis use and achieve abstinence, especially when combined with other therapies like cognitive behavioral therapy. Studies found that CM led to higher abstinence rates in people with cannabis dependence and those with mental health disorders like depression.12345
Is contingency management safe for treating cannabis use and depression?
How is the treatment 'Contingency Management for Cannabis Abstinence' different from other treatments for depression and cannabis use?
Contingency Management is unique because it uses positive reinforcement, like vouchers for goods or services, to encourage cannabis abstinence, which is different from other therapies that might focus on counseling or medication. This approach has shown success in increasing abstinence rates, especially when combined with other therapies like cognitive-behavioral therapy.13678
Eligibility Criteria
This trial is for adolescents aged 12-18 who experience depression or suicidal thoughts and use cannabis. It aims to understand how cannabis affects their mood and risk of suicide, with the goal of creating better interventions.Inclusion Criteria
Exclusion Criteria
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
Baseline
Participants complete a 2-week baseline phase involving real-time, ambulatory smartphone monitoring while using cannabis as usual
Randomized Treatment
Participants are randomized to either 8 weeks of cannabis abstinence with contingency management or non-contingent monitoring with no abstinence requirement
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Contingency management for cannabis abstinence (Behavioral Intervention)
Contingency management for cannabis abstinence is already approved in United States, European Union, Canada for the following indications:
- Substance Abuse Treatment
- Cannabis Use Disorder
- Substance Abuse Treatment
- Cannabis Use Disorder
- Substance Abuse Treatment
- Cannabis Use Disorder