Intermittent Fasting for Type 2 Diabetes

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of Kansas Medical Center

No Placebo Group

Trial Summary

What is the purpose of this trial?

This trial tests whether two types of intermittent fasting can help people with type 2 diabetes manage their blood sugar better. Intermittent fasting may improve how the body uses insulin and lower blood sugar levels. Different types of intermittent fasting have been shown to reduce body weight and improve diabetes parameters such as fasting glucose and fasting insulin. The program includes different phases with varying levels of support over time.

Research Team

Eligibility Criteria

This trial is for adults aged 21-65 with type 2 diabetes diagnosed within the last decade, having a BMI of 25-45 and an HbA1c level between 6.7-9.5%. Participants should be able to exercise and get clearance from the study physician. Those pregnant, lactating, on certain medications, or with recent serious medical issues can't join.

Inclusion Criteria

You can take part in a program that gradually increases physical activity.

I was diagnosed with type 2 diabetes within the last 10 years.

My HbA1c level is between 6.7-9.5%, or it's below 6.7% but I'm on medication to lower it.

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Exclusion Criteria

I have a serious health condition that could make lifestyle changes risky.

I cannot attend health education meetings.

I am on medication that can lower my blood sugar and cannot stop it for the study.

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Treatment Details

Interventions

Intermittent energy restriction (IER) (Behavioral Intervention)
Time Restricted Eating (TRE) (Behavioral Intervention)

Trial OverviewThe trial is examining if intermittent fasting—either Intermittent Energy Restriction (IER) or Time Restricted Eating (TRE)—can help control blood sugar levels in type 2 diabetes patients and possibly lead to remission of the disease.

Participant Groups

2Treatment groups

Experimental Treatment

Group I: Time-restricted eating (TRE)Experimental Treatment1 Intervention

Intermittent fasting using an 8-hour eating period.

Group II: Intermittent energy restriction (IER)Experimental Treatment1 Intervention

Intermittent fasting using a very-low energy diet (VLED; 550-800 kcal/d) 2-3 days per week