~2 spots leftby Apr 2026

Correlation of Bispectral Index Score and Total Intravenous Anesthesia (TIVA)

Recruiting in Palo Alto (17 mi)
SS
Overseen bySteven Shulman, MD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Rutgers, The State University of New Jersey
No Placebo Group

Trial Summary

What is the purpose of this trial?

General Anesthesia is usually produced by an intravenous agent and then maintained with a breathing agent till the surgery is completed. However, there is a recent trend to produce and maintain general anesthesia solely with an intravenous agent, such as propofol, in view of its advantages. This delivery method is called Total Intravenous Anesthesia (TIVA). The depth of general anesthesia can be measured by an anesthetic depth monitoring device called Bispectral Index (BIS). The use of BIS to determine the depth of anesthesia has been well established whenever a breathing agent is used to maintain general anesthesia. However, the validity of using BIS with TIVA has not been adequately investigated. This study will compare the BIS values at different doses of TIVA in order to establish any correlation between the two. If such a correlation is established, BIS monitoring can safely be recommended to determine anesthetic depth under TIVA.

Research Team

SS

Steven Shulman, MD

Principal Investigator

Rutgers/NJMS

Eligibility Criteria

Inclusion Criteria

18-65 undergoing orthopedic or gyn surgery
ASA status I-III

Treatment Details

Interventions

  • Bispectral Index Score (Other)
  • Total Intravenous Anesthesia (TIVA) (Other)

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
University HospitalNewark, NJ
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Who Is Running the Clinical Trial?

Rutgers, The State University of New Jersey

Lead Sponsor

Trials
471
Patients Recruited
81,700+