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Behavioral Intervention

care.coach Avatar™ for Bone Marrow Transplant

N/A
Waitlist Available
Led By Victor Wang, MS
Research Sponsored by care.coach corporation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* Age 18+
* Seen for outpatient RIC HCT (prior to D0, generally D-6).
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 20 (d+20) post-transplant, day 90 (d+90) post-transplant
Awards & highlights

Summary

The overall goal of this study is to assess the efficacy of the care.coach Avatar™ in improving anxiety and quality of life for patients undergoing outpatient transplant. After care.coach Avatar™ content and scheduling ("digital intervention" or "program") has been optimized for outpatient allogeneic hematopoietic stem cell transplantation (HCT), a randomized controlled trial (RCT) will be conducted of the digital versus usual supportive care program for outpatient HCT recipients. Potential improvements in anxiety and quality of life will be evaluated, with the intent of increasing comfortability with outpatient transplant and expanding the population of eligible patients willing to receive their transplants in an outpatient setting.

Who is the study for?
This trial is for patients undergoing outpatient bone marrow transplant (allogeneic hematopoietic stem cell transplantation) who are interested in a digital support program to potentially improve their anxiety and quality of life during the process.
What is being tested?
The study is testing the care.coach Avatar™, a digital intervention designed to provide supportive care. It will be compared with usual supportive care programs to see if it can better help reduce anxiety and enhance quality of life for outpatient HCT recipients.
What are the potential side effects?
Since this trial involves a non-medical intervention (digital support), traditional side effects associated with medications are not expected. However, participants may experience discomfort or dissatisfaction with the technology.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 20 (d+20) post-transplant, day 90 (d+90) post-transplant
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 20 (d+20) post-transplant, day 90 (d+90) post-transplant for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Secondary study objectives
FACT-BMT
HADS-A
Other study objectives
Conversions
HADS-D

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: care.coach Avatar™Experimental Treatment1 Intervention
care.coach Avatar™ with usual supportive care. The avatar program includes companionship, HCT educational modules, relaxation and mindfulness exercises, simple (seated) physical exercises, nightly check ins, and symptom self-management as needed.
Group II: Usual Supportive CareActive Control1 Intervention
Traditional supportive care comprising of a binder with HCT educational materials and regular meetings with a transplant nurse.

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Who is running the clinical trial?

care.coach corporationLead Sponsor
Dana-Farber Cancer InstituteOTHER
1,090 Previous Clinical Trials
343,632 Total Patients Enrolled
Victor Wang, MSPrincipal Investigatorcare.coach corporation
~60 spots leftby Aug 2025
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