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HypErthermia as an Additional Treatment for the Biology and Experience of Depression (HEATBED Trial)

N/A

Waitlist Available

Led By Frederick M Hecht, MD

Research Sponsored by University of California, San Francisco

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 weeks

Awards & highlights

No Placebo-Only Group

Summary

This trial tested the combination of a heat treatment and a type of talk therapy in adults with major depressive disorder. The heat treatment uses heat to potentially boost mood, while the talk therapy helps change negative thoughts. The goal is to find more effective and well-tolerated treatments for depression.

Eligible Conditions

Depression

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Average Number of Planned WBH Sessions Completed

Secondary study objectives

Average Number of Planned Beck Depression Inventory-II (BDI-II) Assessments Completed

Change in Beck Depression Inventory-II (BDI-II) From Baseline to 12-week Assessment

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Cognitive Behavioral Therapy (CBT) and Whole-Body Hyperthermia (WBH)Experimental Treatment2 Interventions

Participants receive up to 8 weekly (early phase) or 4 bi-weekly (later phase) whole-body hyperthermia (WBH) sessions and 8 weekly cognitive behavioral therapy (CBT) sessions. Each WBH session (including preparation and cool down) is up to approximately 3.5-4 hours, and each CBT session is approximately 50 minutes.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Whole-Body Hyperthermia (WBH)

2021

N/A

~20

Cognitive Behavioral Therapy (CBT)

2008

Completed Phase 4

~3620