Holmium vs Thulium Lasers for Kidney Stones
(HOTLaser Trial)

Recruiting in Palo Alto (17 mi)

Overseen byDavid W Sobel, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: MaineHealth

No Placebo Group

Trial Summary

What is the purpose of this trial?

This is a single institution, single surgeon, randomized controlled trial to evaluate the Boston Scientific Lumenis Pulse 120H Moses 2.0 holmium laser versus the Olympus Soltive Superpulsed thulium fiber laser (TFL) for medium-to-large stones in the mini PCNL setting.

Eligibility Criteria

This trial is for individuals with medium-to-large kidney stones who are candidates for a minimally invasive surgical procedure called mini PCNL. Specific eligibility details aren't provided, but typically participants should be in stable health and meet certain criteria set by the surgeon.

Inclusion Criteria

Able to give informed consent

I have kidney stones, with the largest being between 1cm and 3cm.

I am 21 years old or older.

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Exclusion Criteria

Inability to give informed consent

Body Mass Index (BMI) >45

Pregnant or breastfeeding patients

See 9 more

Treatment Details

Interventions

Holmium Laser (Laser Therapy)
Thulium Laser (Laser Therapy)

Trial OverviewThe study compares two types of lasers used in kidney stone surgery: the Boston Scientific Lumenis Pulse 120H Moses 2.0 holmium laser and the Olympus Soltive Superpulsed thulium fiber laser (TFL). Patients will be randomly assigned to one of these treatments.

Participant Groups

2Treatment groups

Active Control

Group I: Thulium LaserActive Control1 Intervention

Participants in this arm are randomized to be treated using the Olympus Soltive SuperPulsed Thulium Fiber Laser

Group II: Holmium LaserActive Control1 Intervention

Participants in this arm are randomized to be treated using the Lumenis Pulse 120H Moses 2.0 Holmium Laser