Trial Summary
What is the purpose of this trial?This trial tests Magnetic Seizure Therapy (MST) for treating depression in patients with Parkinson's Disease. MST uses magnetic pulses to induce controlled seizures, which can help improve mood. The trial aims to see if MST is feasible and safe for these patients. MST is a new treatment that uses magnetic fields to induce therapeutic seizures and has shown promise as an alternative to electroconvulsive therapy (ECT) with potentially fewer cognitive side effects.
Eligibility Criteria
This trial is for people over 50 with Parkinson's Disease who are experiencing depression. They must be able to consent, on stable medication, and fit the criteria for a major depressive episode. They can't join if they have unstable medical conditions, difficulty with English or sensory impairments affecting tests, certain cardiovascular risks, recent psychotropic meds changes, active psychosis, metal implants near the head or high benzodiazepine/anticonvulsant doses.Inclusion Criteria
You are 50 years of age or older.
Outpatient or inpatient persons capable of providing informed consent
On stable doses of psychotropic medication
+8 more
Exclusion Criteria
Unstable medical conditions that, in the opinion of the Principal Investigator, carries significant risk of exacerbation by either of the study interventions
Unable to communicate in English fluently enough to complete the neuropsychological tests
Have a non-correctable clinically significant sensory impairment (i.e., cannot hear or see well enough to complete the neuropsychological tests)
+6 more
Participant Groups
The trial is testing Magnetic Seizure Therapy (MST) as a treatment for depression in Parkinson's patients. Participants will undergo MST sessions while keeping their current antidepressant treatment constant if applicable.
1Treatment groups
Experimental Treatment
Group I: Magnetic Seizure TherapyExperimental Treatment1 Intervention
MST treatments will be administered using the MagPro XP MST with Cool TwinCoil.
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
University of British ColumbiaVancouver, Canada
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Who Is Running the Clinical Trial?
University of British ColumbiaLead Sponsor