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Antiplatelet agent

Patients with STEMI treated medically for Heart Attack

N/A
Waitlist Available
Led By Bo YU, MD,PhD
Research Sponsored by Harbin Medical University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1, 3, 6, 9, 12 months after pci
Awards & highlights

Summary

This protocol describes a prospective, multi-center study intended to test the hypothesis that patients with STEMI caused by plaque rupture or plaque erosion without obstructive stenosis (diameter stenosis \<70%) can be stabilized by effective antithrombotic treatment without stent implantation, thereby avoiding both early and late complications related to percutaneous coronary intervention (PCI) with stent implantation. All the patients will be followed by intracoronary OCT and physiological assessment at 1-month and 12-month follow-up.

Eligible Conditions
  • Heart Attack

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 and 12 months after pci
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 and 12 months after pci for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Reduction of thrombus burden assessed by OCT
Secondary study objectives
Effective flow area increase
Fractional flow reserve
Major cardiovascular adverse events

Trial Design

1Treatment groups
Experimental Treatment
Group I: Patients with STEMI treated medicallyExperimental Treatment1 Intervention
Drug: dual antiplatelet therapy (aspirin + ticagrelor or aspirin + clopidogrel) for at least 12 months.

Find a Location

Who is running the clinical trial?

Harbin Medical UniversityLead Sponsor
96 Previous Clinical Trials
62,697 Total Patients Enrolled
Shenzhen Salubris Pharmaceuticals Co., Ltd.Industry Sponsor
12 Previous Clinical Trials
3,171 Total Patients Enrolled
Beijing Luhe HospitalOTHER
31 Previous Clinical Trials
32,922 Total Patients Enrolled
~40 spots leftby Sep 2025
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