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Calcium Channel Blocker

Amlodipine for Hypertension

Phase 4
Waitlist Available
Research Sponsored by Prisma Health-Upstate
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through hospital stay, on average 2-5 days
Awards & highlights

Study Summary

This trial is testing if amlodipine is just as effective as nifedipine ER in managing hypertension in postpartum women.

Eligible Conditions
  • Pregnancy-Induced Hypertension (PIH)

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through hospital stay, on average 2-5 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and through hospital stay, on average 2-5 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Length of stay
Secondary outcome measures
Breastfeeding duration
Antihypertensive Agents
Number of patients discontinuing medication due to side effects
+3 more

Side effects data

From 2019 Phase 4 trial • 44 Patients • NCT02034435
13%
IV infiltration or malfunction
6%
Pain
100%
80%
60%
40%
20%
0%
Study treatment Arm
Aim 2- Amlodipine
Aim 1- Low Sodium
Aim 2- Eplerenone
Aim 1- High Sodium

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: AmlodipineExperimental Treatment1 Intervention
Group II: Nifedipine ERActive Control1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Amlodipine
FDA approved

Find a Location

Who is running the clinical trial?

Prisma Health-UpstateLead Sponsor
83 Previous Clinical Trials
42,896 Total Patients Enrolled
1 Trials studying Hypertension
202 Patients Enrolled for Hypertension
~32 spots leftby Jun 2025
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