~12 spots leftby Jul 2026

Gait Retraining for Knee Osteoarthritis

Recruiting in Palo Alto (17 mi)
MA
Overseen byMichael A Hunt, PT, PhD
Age: 18+
Sex: Female
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: University of British Columbia
No Placebo Group

Trial Summary

What is the purpose of this trial?

Tibiofemoral osteoarthritis (TFOA) is highly prevalent in older adults, and often causes symptoms and functional limitations. Physical activity is widely advocated in people with TFOA, and running is an easy and accessible activity that provides many benefits on general health. However, running induces high knee loads, which could potentially contribute to symptoms of runners with TFOA. Previous studies have suggested that running gait modifications can help in decreasing symptoms and knee loading in runners with knee conditions. Yet, no study has been conducted in runners with TFOA. This intervention study will investigate the effects of a 4-week running gait retraining program on symptoms and running biomechanics in runners with TFOA. We hypothesize that running modifications will decrease symptoms, improve function and reduce knee loading.

Research Team

MA

Michael A Hunt, PT, PhD

Principal Investigator

University of British Columbia

Eligibility Criteria

This trial is for adult runners who have mild to moderate knee osteoarthritis, run at least 10 km weekly for over six months, can comfortably run on a treadmill for 30 minutes, and experience knee pain most days. It's not suitable for non-English speakers, those with recent serious knee injuries or certain medications, heart conditions that make running unsafe, or other leg issues affecting running.

Inclusion Criteria

I have experienced knee pain of at least 3 out of 10 nearly every day last month.
My arthritis is mild to moderate according to the Kellgren and Lawrence scale.
You have been consistently running for at least 6 months, covering a distance of 10 kilometers every week.
See 1 more

Exclusion Criteria

I haven't used any corticosteroids or viscosupplementation in the last 6 months.
I do not speak English.
I have heart or lung conditions that prevent me from safely doing moderate running.
See 4 more

Treatment Details

Interventions

  • Gait retraining (Behavioral Intervention)
Trial OverviewThe study tests a 4-week program designed to change how people with knee osteoarthritis run (gait retraining). The goal is to see if these changes can reduce their symptoms like pain and improve their ability to function without putting too much stress on the knees.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Gait retrainingExperimental Treatment1 Intervention
Runners will be taught how to modify their running gait through multiple laboratory sessions and in-field training.

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of British Columbia

Lead Sponsor

Trials
1,506
Recruited
2,528,000+
Dr. Christopher Haqq profile image

Dr. Christopher Haqq

University of British Columbia

Chief Medical Officer since 2019

MD, University of British Columbia

Bekki Bracken Brown profile image

Bekki Bracken Brown

University of British Columbia

Chief Executive Officer since 2023

Bachelor's degree from Duke University