Regular vs Clear Liquid Diet for Pancreatitis

Recruiting in Palo Alto (17 mi)

Overseen byJames Buxbaum, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of Southern California

No Placebo Group

Trial Summary

What is the purpose of this trial?

Acute pancreatitis is among the most common gastroenterology diagnosis in the United States, and represents a large economic burden to the United States health system. While recent guidelines agree early feeding shortens length of stay, these guidelines fail to provide recommendations on optimal diet to start leaving diet type to clinician discretion. Therefore, the aim is to assess the comparative efficacy of full calorie regular diet (RD) versus clear liquid diet (CLD) on length of hospital stay (LOHS) for mild to moderate acute pancreatitis (AP). The study population will target mild to moderate acute pancreatitis patients who can tolerate eating in a single institution. The primary end point will focus on LOHS, and secondary end points will include Pancreatic Activity Scoring System, side effects and readmission.

Research Team

James Buxbaum, MD

Principal Investigator

Eligibility Criteria

This trial is for adults over 18 with mild to moderate acute pancreatitis, confirmed by specific diagnostic criteria. It's not for pregnant or breastfeeding women, those unable to consent, transferred from other hospitals, with chronic/severe pancreatitis, certain etiologies like hypertriglyceridemia or trauma, and those who can't eat orally due to other medical issues.

Inclusion Criteria

I have acute pancreatitis according to the Atlanta Criteria.

I am 18 years old or older.

Exclusion Criteria

Patients transferred from another hospital

My high triglycerides are not due to trauma, autoimmune pancreatitis, or other causes.

I had surgery for infected pancreatic tissue or bleeding.

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Treatment Details

Interventions

Clear Liquid Diet (Behavioural Intervention)
Regular diet (Behavioural Intervention)

Trial OverviewThe study compares the effects of a full calorie regular diet (RD) versus a clear liquid diet (CLD) on hospital stay length in patients with mild to moderate acute pancreatitis. The main goal is seeing if one diet type helps patients leave the hospital sooner.

Participant Groups

2Treatment groups

Active Control

Group I: Regular DietActive Control1 Intervention

Patient randomized to regular diet will begin with a regular diet.

Group II: Clear Liquid DietActive Control1 Intervention

Patient randomized to clear liquid diet will begin with a clear liquid diet.