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Behavioural Intervention

Exercise Program for Parkinson's Disease (LifePD Trial)

N/A
Waitlist Available
Led By Robert Motl, PhD
Research Sponsored by University of Illinois at Chicago
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age of 50+ years
Self-reported ability to ambulate without assistance
Timeline
Screening 3 weeks
Treatment Varies
Follow Up changes in perceived social support for self-efficacy from baseline (pre-intervention) to after 16 weeks (post-intervention)
Awards & highlights
No Placebo-Only Group

Summary

This trial will test a 16-week exercise program for people with Parkinson's disease who are not physically active. Participants will be randomly assigned to either a combined aerobic and resistance exercise group or a flexibility and

Who is the study for?
This trial is for physically inactive individuals with Parkinson's Disease who are interested in improving their physical activity, cognitive function, symptoms, and quality of life. Participants will engage in a 16-week program from home using Zoom and must be willing to follow the exercise or stretching routines provided.
What is being tested?
The study tests a social-cognitive theory-based behavioral intervention that includes aerobic and resistance exercises (GET Up PD) against an active control group doing flexibility and stretching. It aims to see if the exercise training can improve physical activity levels, cognitive functions, symptoms, and quality of life over 16 weeks.
What are the potential side effects?
While not explicitly mentioned, potential side effects may include muscle soreness or strain from exercise activities. As it's a remotely-delivered program focusing on increasing physical activity safely at home, serious side effects are unlikely but participants should report any discomfort.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am 50 years old or older.
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I can walk on my own without help.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~changes in scopa-cog baseline (pre-intervention) to after 16 weeks (post-intervention)
This trial's timeline: 3 weeks for screening, Varies for treatment, and changes in scopa-cog baseline (pre-intervention) to after 16 weeks (post-intervention) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Physical Activity
Secondary study objectives
Anxiety
Cognitive Function
Depressive Symptoms
+4 more
Other study objectives
Social Cognitive Theory

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: GET Up PDExperimental Treatment1 Intervention
Remotely-coached/guided, home-based program delivered using telerehabilitation focusing on aerobic fitness and muscle strength as a mode of training
Group II: Stretching and FlexibilityActive Control1 Intervention
Remotely-coached/guided, home-based program delivered using telerehabilitation focusing on stretching and range of motion as the mode of training

Find a Location

Who is running the clinical trial?

University of Illinois at ChicagoLead Sponsor
640 Previous Clinical Trials
1,568,658 Total Patients Enrolled
National Institute on Aging (NIA)NIH
1,805 Previous Clinical Trials
28,194,807 Total Patients Enrolled
Robert Motl, PhDPrincipal InvestigatorUniversity of Illinois at Chicago
2 Previous Clinical Trials
64 Total Patients Enrolled
~33 spots leftby Jan 2026