Personality-Based Therapy for Borderline Personality Disorder
Recruiting in Palo Alto (17 mi)
Overseen byShannon Sauer-Zavala, PhD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Recruiting
Sponsor: Shannon E. Sauer-Zavala
Disqualifiers: Psychological conditions, Psychotherapy, Substance use, others
No Placebo Group
Approved in 3 Jurisdictions
Trial Summary
What is the purpose of this trial?Participants with borderline personality disorder will undergo an a 2 - 4 week baseline assessment to determine level of outcomes of interest in the absence of treatment. After the baseline period, participants will receive six weekly 50-60-minute treatment sessions. After the 6 treatment sessions, participants will complete a 4-week follow-up period to determine the sustainability of the treatment module.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it mentions 'medication instability' as an exclusion criterion, which might mean your medication needs to be stable before joining.
What data supports the effectiveness of the treatment Personality-Based Therapy for Borderline Personality Disorder?
Research shows that therapies like Dialectical Behavior Therapy (DBT) and Mentalization-Based Therapy (MBT) are effective for treating Borderline Personality Disorder, helping improve emotional regulation and interpersonal relationships.
12345Is Personality-Based Therapy safe for humans?
Personality-Based Therapy, including Dialectical Behavior Therapy (DBT) and Mentalization-Based Therapy (MBT), is widely used and considered safe for treating borderline personality disorder. These therapies are evidence-based and have been implemented in various settings, indicating their general safety in humans.
16789How is Personality-Based Therapy different from other treatments for borderline personality disorder?
Personality-Based Therapy for borderline personality disorder is unique because it combines several evidence-based treatments like Dialectical Behavior Therapy (DBT) and Mentalization-Based Therapy (MBT), which focus on improving emotional regulation and understanding others' perspectives. This approach is distinct in its comprehensive integration of multiple therapeutic techniques tailored to individual needs, unlike standard treatments that may focus on a single method.
1581011Eligibility Criteria
This trial is for English-speaking individuals diagnosed with Borderline Personality Disorder. It's not suitable for those who have other psychological conditions needing different treatments, are currently in psychotherapy, have substance use disorders, or whose medication use isn't stable.Inclusion Criteria
Speak English fluently
I have been diagnosed with Borderline Personality Disorder.
Exclusion Criteria
I am currently undergoing psychotherapy.
My medication doses have been stable recently.
I have a mental health condition that needs different treatment.
+1 more
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
2-4 weeks
Baseline Assessment
Participants undergo a 2-4 week baseline assessment to determine level of outcomes of interest in the absence of treatment
2-4 weeks
Treatment
Participants receive six weekly 50-60-minute treatment sessions tailored to 1 of 3 personality dimensions
6 weeks
Follow-up
Participants are monitored for sustainability of the treatment module after the treatment sessions
4 weeks
Participant Groups
The study tests a new therapy specifically designed for personality changes in people with Borderline Personality Disorder. Participants will first be observed without treatment and then receive six weekly sessions of the therapy to see its effects.
2Treatment groups
Experimental Treatment
Group I: Personality-based treatment 4 week baselineExperimental Treatment1 Intervention
Participants will receive treatment tailored to 1 of 3 personality dimensions after a 4 week baseline assessment
Group II: Personality-based treatment 2 week baselineExperimental Treatment1 Intervention
Participants will receive treatment tailored to 1 of 3 personality dimensions after a 2 week baseline assessment
Personality-Based Therapy is already approved in United States, European Union, Canada for the following indications:
🇺🇸 Approved in United States as Personality-Based Therapy for:
- Borderline Personality Disorder
🇪🇺 Approved in European Union as Personality-Based Therapy for:
- Borderline Personality Disorder
🇨🇦 Approved in Canada as Personality-Based Therapy for:
- Borderline Personality Disorder
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Clinic for Emotional Health at the University of KentuckyLexington, KY
Loading ...
Who Is Running the Clinical Trial?
Shannon E. Sauer-ZavalaLead Sponsor
National Institute of Mental Health (NIMH)Collaborator
American Psychological FoundationCollaborator
References
Patient experiences of therapy for borderline personality disorder: Commonalities and differences between dialectical behaviour therapy and mentalization-based therapy and relation to outcomes. [2022]Dialectical behaviour therapy (DBT) and mentalization-based therapy (MBT) are widely used evidence-based psychological treatments for borderline personality disorder (BPD). The study aimed to establish evidence on common and unique, and helpful and unhelpful, treatment processes.
Specialized psychotherapies for adults with borderline personality disorder: A systematic review and meta-analysis. [2019]Borderline personality disorder affects up to 2% of the population and is associated with poor functioning, low quality of life and increased mortality. Psychotherapy is the treatment of choice, but it is unclear whether specialized psychotherapies (dialectical behavior therapy, mentalization-based treatment, transference-focused therapy and schema therapy) are more effective than non-specialized approaches (e.g. protocolized psychological treatment, general psychiatric management). The aim of this systematic review is to investigate the effectiveness of these psychotherapies.
Mentalization-based treatment or psychodynamic treatment programmes for patients with borderline personality disorder - the impact of clinical severity. [2020]Mentalization-based treatment (MBT), originally designed for patients with borderline personality disorder (BPD), may be particularly indicated for severe conditions. However, there is limited documentation of how increasing severity of personality disorder (PD) effect outcomes of highly specialized treatments. This study aimed to investigate associations between clinical severity and outcomes for patients in MBT as compared to a psychodynamic group-based treatment programme (PDT).
Mentalization-Based Treatment for Personality Disorders: Efficacy, Effectiveness, and New Developments. [2020]This review aims to outline the most recent evidence on the efficacy and effectiveness of mentalization-based treatment (MBT) for personality disorders (PD) from 2015 to 2018 and to describe new treatment developments.
Dialectical behaviour therapy v. mentalisation-based therapy for borderline personality disorder. [2022]Dialectical behaviour therapy (DBT) and mentalisation-based therapy (MBT) are both widely used evidence-based treatments for borderline personality disorder (BPD), yet a head-to-head comparison of outcomes has never been conducted. The present study therefore aimed to compare the clinical outcomes of DBT v. MBT in patients with BPD.
Evaluation of a Dialectical Behavior Therapy Psychiatry Residency Training Program. [2022]Dialectical behavior therapy (DBT) is a widely disseminated evidence-based treatment for patients with borderline personality disorder (BPD). This evaluation of a community psychiatry residency rotation compared a DBT training program to a standard care training program to determine the levels of confidence in treating patients with BPD, willingness to treat patients with BPD, and attitudes towards this patient population.
Implementing dialectical behavior therapy. [2022]Dialectical behavior therapy (DBT) is a cognitive-behavioral approach to treating borderline personality disorder. Early empirical results are promising, although they are not sufficient to establish DBT as an evidence-based practice in community settings. Nevertheless, the treatment has been widely implemented by mental health authorities, program leaders, and clinicians. The authors describe DBT's four stages of treatment, the functional areas addressed, and the treatment modes used as well as the reasons for the appeal of DBT to practitioners. They review barriers encountered by those who have implemented the model and present strategies that have been developed to overcome the barriers.
Short-Term versus Long-Term Mentalization-Based Therapy for Borderline Personality Disorder: A Randomized Clinical Trial (MBT-RCT). [2023]Borderline personality disorder (BPD) is a severe and prevalent psychiatric disorder. Mentalization-based therapy (MBT) is an evidence-based intervention for BPD, and several countries offer treatment programs for BPD lasting for years, which is resource demanding. No previous trial has compared short-term with long-term MBT.
Dialectical behavior therapy for personality disorders. [2019]Interest in dialectical behavior therapy (DBT) as a treatment for personality disorders has increased dramatically in recent years. Although originally designed for the outpatient treatment of suicidal individuals with borderline personality disorder (BPD), DBT has been applied to many more diverse populations including comorbid substance dependence and BPD, inpatient treatment for BPD, as well as antisocial behaviors in juveniles and adults. This paper provides a brief overview of DBT, presents and evaluates the most recent literature on the application of DBT to the treatment of personality disorders, and highlights some of the current controversies surrounding the use of DBT.
Day hospital versus intensive out-patient mentalisation-based treatment for borderline personality disorder: multicentre randomised clinical trial. [2021]Two types of mentalisation-based treatment (MBT) have been developed and empirically evaluated for borderline personality disorder (BPD): day hospital MBT (MBT-DH) and intensive out-patient MBT (MBT-IOP). No trial has yet compared their efficacy.
Pedagogical stance in mentalization-based treatment. [2022]A common aspect of evidence-based treatments for people with borderline personality disorder (BPD) is pedagogical interventions and formats. In mentalization-based treatment (MBT) the introductory course has a clear pedagogical format, but a pedagogical stance is not otherwise defined.