Dietary Intervention for Prediabetes
Trial Summary
What is the purpose of this trial?
1 in 3 adults have prediabetes in the United States, and many of them will eventually develop diabetes, which has significant public health and economic costs. However, type 2 diabetes (T2D) and prediabetes are heterogeneous groups with different pathological mechanisms, dysfunctions in different processes, and varied disease trajectories. Patient stratifications into subtypes and personalized nutrition interventions are highly needed but not yet available. Metabolic responses (e.g., glucose excursion) after food intake provide a direct observation of personal metabolic control and its association with T2D. The investigators hope to learn how prediabetes and type 2 diabetes evolve, and specifically what food or exercise can do to mitigate blood sugar response.
Eligibility Criteria
This trial is for generally healthy adults over 18 living near Stanford who have prediabetes or type 2 diabetes managed by diet or metformin. Participants must not be pregnant, have cognitive impairments, malabsorptive disorders, major organ diseases, a history of bariatric surgery, heavy alcohol use, recent significant weight change, or be on certain medications.Inclusion Criteria
Exclusion Criteria
Treatment Details
Interventions
- Dietary intervention (Behavioural Intervention)