Trial Summary
What is the purpose of this trial?The overarching goal of this trial is to develop mechanisms to improve cardiovascular care among such prostate cancer patients receiving ADT by increasing patient awareness of individualized cardiovascular risk estimates and mitigation opportunities. Patients will be given access to a web-based quality improvement tool to educate patients of cardiovascular risks in prostate cancer and to inform them of their individualized, estimated cardiovascular risk and guideline-based risk mitigation recommendations.
The study will assess the feasibility of this web-based application as a cardiovascular education tool for patients with prostate cancer.
The study will also evaluate if completion of the web-based tool improves cardiovascular care access and risk mitigation for patients with prostate cancer.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the CARE-PC Web-Based Application treatment for cardiovascular care in prostate cancer?
The effectiveness of web-based tools in prostate cancer care is supported by studies showing that electronic patient-reported outcomes (ePRO) can improve communication with doctors and enhance patient health. Additionally, decision aids like the Personal Patient Profile-Prostate (P3P) have been shown to reduce decisional conflict in prostate cancer patients, suggesting that similar web-based applications could be beneficial.
12345How does the web-based tool for cardiovascular care in prostate cancer differ from other treatments?
This web-based tool is unique because it focuses on electronic patient-reported outcomes and holistic needs assessment, allowing for personalized and continuous care through remote monitoring and support, unlike traditional paper-based methods.
36789Eligibility Criteria
This trial is for men over 18 with prostate cancer who are currently on or will start androgen deprivation therapy (ADT) for at least six months. Participants need to be able to read and understand English.Inclusion Criteria
Patients must be able to read and understand English.
I am a man over 18 with prostate cancer and will be on hormone therapy for at least 6 months.
Exclusion Criteria
n/a
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
2-4 weeks
Web-Based Application Participation
Participants use a web-based tool to learn about cardiovascular risks and receive individualized risk estimates and mitigation recommendations
6 months
Online participation
Follow-up
Participants are monitored for changes in cardiovascular care and medication adjustments
18 months
Participant Groups
The CARE-PC study is testing a web-based application designed to educate prostate cancer patients about their cardiovascular risks associated with ADT, provide personalized risk assessments, and offer guidelines for risk reduction.
1Treatment groups
Experimental Treatment
Group I: Men With Prostate Cancer Planned for Receiving ADTExperimental Treatment1 Intervention
Men with prostate cancer \> 18 years of age who are currently receiving or will be receiving treatment with ≥ 6 months of systemic androgen deprivation therapy (ADT).
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, PA
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Who Is Running the Clinical Trial?
Vivek NarayanLead Sponsor
National Comprehensive Cancer NetworkCollaborator
References
An electronic registry to improve adherence to active surveillance monitoring among men with prostate cancer at a safety-net hospital: protocol for a pilot study. [2022]The evidence-based practice of active surveillance to monitor men with favorable-risk prostate cancer in lieu of initial definitive treatment is becoming more common. However, there are barriers to effective implementation, particularly in low-resource settings. Our goal is to assess the efficacy and feasibility of a health information technology registry for men on active surveillance at a safety-net hospital to ensure patients receive guideline-recommended care.
Decision Support with the Personal Patient Profile-Prostate: A Multicenter Randomized Trial. [2019]We evaluated the efficacy of the web based P3P (Personal Patient Profile-Prostate) decision aid vs usual care with regard to decisional conflict in men with localized prostate cancer.
Electronic patient-reported outcome (ePRO) application for patients with prostate cancer. [2023]Cancer patients experience different complications and outcomes during or after medical treatments. Electronic reporting of the outcomes by patients is a solution that facilitates communication with physicians and improve patient health status. The aim of this study was to develop a smartphone-based application for electronic reporting of outcomes by patients with prostate cancer.
Receipt of best care according to current quality of care measures and outcomes in men with prostate cancer. [2021]We evaluated whether patients with prostate cancer who received best care according to a set of 5 nationally endorsed quality measures had decreased treatment related morbidity and improved cancer control.
Digital Medicine in Men with Advanced Prostate Cancer - A Feasibility Study of Electronic Patient-reported Outcomes in Patients on Systemic Treatment. [2022]Electronic patient-reported outcome (ePRO) measures have the potential to improve patient care, both at an individual level by detecting symptoms and at an organisational level to rationalise follow-up. The introduction of ePROs has many challenges, including funding, institutional rigidity and acceptability for both patients and clinicians. There are multiple examples of successful ePRO programmes but no specific feasibility studies in those who are less digitally engaged. Prostate cancer is predominantly a disease of older men and digital exclusion is associated with increased age. We assessed the feasibility of ePRO completion in older men receiving treatment for advanced prostate cancer both within the clinic and from home.
Patients' experiences of using an e-Health tool for self-management support after prostate cancer surgery: a deductive interview study explained through the FITT framework. [2021]To evaluate patients' experiences of using a web-based application, especially its usability as support for self-care activities after prostate cancer surgery.
A Web-Based Prostate Cancer-Specific Holistic Needs Assessment (CHAT-P): Multimethod Study From Concept to Clinical Practice. [2022]Men with prostate cancer experience immediate and long-term consequences of the disease and its treatment. They require both long-term monitoring for recurrence or progression and follow-up to identify and help manage psychosocial and physical impacts. Holistic Needs Assessment aims to ensure patient-centered continuing cancer care. However, paper-based generic tools have had limited uptake within cancer services, and there is little evidence of their impact. With the expansion of remote methods of care delivery and to enhance the value of generic tools, we developed a web-based Composite Holistic Needs Assessment Adaptive Tool-Prostate (CHAT-P) specifically for prostate cancer.
The Internet and prostate cancer patients: searching for and finding information. [2018]To define the characteristics of prostate cancer patients who use the Internet.
Examining the Priorities, Needs and Preferences of Men with Metastatic Prostate Cancer in Designing a Personalised eHealth Exercise Intervention. [2022]Few individuals with metastatic prostate cancer have access to prostate cancer-specific exercise support, despite demonstrated benefits. eHealth tools, such as websites, may be viable options for increasing access. To be effective and acceptable, future eHealth websites need to consider end-users' perspectives, capacity and needs. We aim to provide insight into these factors by exploring daily priorities, activities and health literacy of individuals with metastatic prostate cancer and their perspectives towards exercise and exercise-based web-based eHealth interventions.