Inspiratory Muscle Training for Lung Transplant Recovery

Recruiting in Palo Alto (17 mi)

Overseen byCristiane Meirelles, PT, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Ohio State University

No Placebo Group

Trial Summary

What is the purpose of this trial?

This trial is testing a special breathing exercise device for people who have had a lung transplant. The device helps strengthen the muscles used for breathing. The goal is to help these patients breathe better, feel less tired, and improve their ability to do everyday activities.

Research Team

Cristiane Meirelles, PT, PhD

Principal Investigator

School of Health and Rehabilitation Sciences- Physical Therapy Division

Eligibility Criteria

This trial is for people waiting for a lung transplant who can walk (even with help) and understand the study. They shouldn't have cognitive issues that make it hard to follow instructions or already be doing inspiratory muscle training.

Inclusion Criteria

I can walk by myself or with help from a device.

Participant has personally signed and dated informed consent form indicating understanding of all pertinent aspects of the study

You are waiting for a lung transplant.

Exclusion Criteria

I struggle to understand or follow instructions due to cognitive issues.

You are currently enrolled in a regular IMT program.

Treatment Details

Interventions

PowerBreathe Medic (Behavioural Intervention)

Trial OverviewThe study tests if using an inspiratory muscle trainer right after a lung transplant helps patients breathe better, feel less tired, and improve their daily activities compared to those who only get standard physical therapy.

Participant Groups

3Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: Inspiratory Muscle training- Intervention groupExperimental Treatment1 Intervention

Along with standard post-transplant physical therapy, the intervention group will begin daily respiratory exercise training utilizing the IMT trainer device (POWERbreathe Medic Plus®) with weekly incremental increases in respiratory load. Patients will be asked to use the IMT device twice per day, 7 days per week, for 8 weeks.

Group II: Usual care groupActive Control1 Intervention

Patients will only participate in standard post-transplant physical therapy.

Group III: Inspiratory Muscle training - Placebo groupPlacebo Group1 Intervention

Along with standard post-transplant physical therapy, the placebo group will begin daily respiratory exercise training utilizing the IMT trainer device (POWERbreathe Medic Plus®) with no increase of respiratory load. Patients will be asked to use the IMT device twice per day, 7 days per week, for 8 weeks.