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nCPAP for Respiratory Insufficiency (HHFNC Trial)

N/A
Waitlist Available
Led By Bradley A Yoder, MD
Research Sponsored by University of Utah
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Summary

We hypothesize that the success rate for keeping babies extubated (without a breathing tube for assisted mechanical ventilation), defined as the proportion of infants remaining extubated for a minimum of 72 hours, will be equivalent among infants managed with nasal CPAP compared to humidified high flow nasal cannula (HHFNC).

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Trial Design

2Treatment groups
Active Control
Group I: nCPAPActive Control2 Interventions
Infants randomized to the nasal Continuous Positive Airway Pressure (nCPAP) treatment group
Group II: HHFNCActive Control2 Interventions
Infants randomized to the Humidified High Flow Nasal Cannula (HHFNC) treatment group post extubation

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Who is running the clinical trial?

University of UtahLead Sponsor
1,127 Previous Clinical Trials
1,792,777 Total Patients Enrolled
6 Trials studying Respiratory Insufficiency
3,073 Patients Enrolled for Respiratory Insufficiency
Intermountain Health Care, Inc.OTHER
139 Previous Clinical Trials
1,963,540 Total Patients Enrolled
2 Trials studying Respiratory Insufficiency
8,938 Patients Enrolled for Respiratory Insufficiency
Bradley A Yoder, MDPrincipal InvestigatorUniversity of Utah
1 Previous Clinical Trials
15 Total Patients Enrolled
~24 spots leftby Sep 2025
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