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Stress Impact for Rosacea
N/A
Recruiting
Led By Kristen Metzler-Wilson, PT, PhD
Research Sponsored by Kristen Metzler-Wilson
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up immediate (during the single-day study). this study consists of a one-day protocol, during which this outcome is measured.
Awards & highlights
No Placebo-Only Group
Summary
This trial seeks to understand how stress can trigger rosacea symptoms to inform treatments for the 16 million Americans it affects.
Who is the study for?
This trial is for healthy males and females with mild to moderate rosacea, who are not pregnant or breastfeeding. Participants should not have any major health issues like heart or neurological disorders, no recent drug/alcohol abuse, no allergies to protocol drugs, non-smokers, and a BMI under 35.
What is being tested?
The study investigates how stressors affecting the 'fight or flight' nervous system contribute to rosacea symptoms. It aims to improve understanding of this relationship in order to develop better treatments for those suffering from rosacea.
What are the potential side effects?
Since the trial involves studying the effects of systemic and local stressors on individuals with rosacea rather than testing new medications, specific side effects are not listed but may include temporary increased redness or inflammation.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ immediate (during the single-day study). this study consists of a one-day protocol, during which this outcome is measured.
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediate (during the single-day study). this study consists of a one-day protocol, during which this outcome is measured.
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Skin blood flow
Skin sympathetic nerve activity
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
1Treatment groups
Experimental Treatment
Group I: Autonomic responses to stressorsExperimental Treatment1 Intervention
Protocol 1: mental math and handgrip exercise. Protocol 2: systemic stressors and end-organ receptor stimulation. Protocol 3: local heating.
Find a Location
Who is running the clinical trial?
Kristen Metzler-WilsonLead Sponsor
Marian UniversityOTHER
Indiana UniversityLead Sponsor
1,044 Previous Clinical Trials
1,316,659 Total Patients Enrolled
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NIH
502 Previous Clinical Trials
1,089,808 Total Patients Enrolled
Kristen Metzler-Wilson, PT, PhDPrincipal Investigator - University of Kentucky
Indiana University