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Stem Cell Therapy

Bone Marrow Stem Cells for Rotator Cuff Tears

N/A
Waitlist Available
Led By Matthew J Best, MD
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 2 years.
Awards & highlights
No Placebo-Only Group

Summary

This trial is comparing the benefits of using different amounts of bone marrow from the upper arm in repairing a shoulder tendon.

Who is the study for?
This trial is for individuals with rotator cuff tears. Specific eligibility details are not provided, but typically participants would need to be in good health otherwise and able to undergo the procedures involved in the trial.
What is being tested?
The study is testing two methods of repairing rotator cuffs: one using whole bone marrow and another using concentrated bone marrow from the upper arm bone. It's a randomized controlled trial, meaning patients are randomly assigned to either method to compare outcomes.
What are the potential side effects?
While specific side effects aren't listed, common risks may include pain at the injection site, infection, bleeding or bruising. There could also be complications related to anesthesia or reactions specific to stem cell treatments.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 2 years.
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 2 years. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Number of Rotator cuff re-tears as assessed by magnetic resonance imaging
Secondary study objectives
American Shoulder and Elbow Surgeons Score
Comprehensive Shoulder Assessment
Rate of oral and/or intra-articular corticosteroid required
+3 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Bone marrow concentrateExperimental Treatment1 Intervention
20cc of whole bone marrow concentrated (varying quantities)
Group II: 20cc bone marrow aspirateExperimental Treatment1 Intervention
Bone marrow aspirate, 20cc
Group III: 4cc bone marrow aspirateActive Control1 Intervention
Bone marrow aspirate, 4cc

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor
2,326 Previous Clinical Trials
14,874,579 Total Patients Enrolled
1 Trials studying Rotator Cuff Tears
ON FoundationUNKNOWN
Uma Srikumaran, MD, MBA, MPHStudy DirectorJohns Hopkins University
~100 spots leftby Jul 2026
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