SEPSys and RESCUE Scores for Sepsis Prediction

Recruiting in Palo Alto (17 mi)

+7 other locations

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of Maryland, Baltimore

No Placebo Group

Trial Summary

What is the purpose of this trial?

This study is designed to test two new risk scores - one designed to predict a patient's four-hour risk of developing sepsis and one designed to predict a patient's four-hour risk of deterioration (cardiac arrest, death, unplanned ICU transfer, or rapid response team call). The goal of this study is to improve provider awareness of a patient's risk of these two negative outcomes by providing them with new risk scores. The primary outcome will be the time from when the risk score becomes elevated to when vital signs such as heart rate or blood pressure are measured, suggesting an increased awareness.

Research Team

Eligibility Criteria

This trial is for patients at risk of sepsis or sudden health decline, including conditions like umbilical sepsis and pre-eclampsia. Specific inclusion and exclusion criteria are not detailed here.

Inclusion Criteria

Additional RESCUE Encounter Inclusion Criteria: Encounter has a RESCUE Score

Hospital Unit Inclusion Criteria: Units are part of a member hospital of the University of Maryland Medical System (UMMS)

Units agree to participate in the study

Exclusion Criteria

Additional RESCUE Encounter Exclusion Criteria: Encounter is admitted with a high RESCUE Score (RESCUE Score of 4)

My treatment center focuses on children under 18.

I was admitted to the hospital with sepsis.

Treatment Details

Interventions

• RESCUE Score (Behavioural Intervention)
• UMMS Sepsis Early Prediction Score (SEPSys) (Behavioural Intervention)

Trial Overview The study tests two new scores: SEPSys predicts the four-hour risk of developing sepsis, while RESCUE predicts the same timeframe risk of deterioration (like cardiac arrest). It aims to alert healthcare providers early.

Participant Groups

Group I: SEPSys+RESCUE Experimental Treatment 2 Interventions

Cluster has both SEPSys \& RESCUE Scores

Group II: SEPSys Experimental Treatment 1 Intervention

Cluster has SEPSys Score only

Group III: RESCUE Experimental Treatment 1 Intervention

Cluster has RESCUE Score only

Group IV: Baseline Active Control 1 Intervention

Cluster has neither SEPSys nor RESCUE

Find a Clinic Near You

Research Locations Nearby Select from list below to view details:

University of Maryland Medical Center - Midtown Baltimore, MD

University of Maryland Medical Center Baltimore, MD

University of Maryland Upper Chesapeake Medical Center Bel Air, MD

University of Maryland Shore Medical Center Easton, MD

More Trial Locations

Who Is Running the Clinical Trial?

University of Maryland, Baltimore

Lead Sponsor

Trials

729

Patients Recruited

540,000+

University of Maryland Medical System

Collaborator

Trials

2

Patients Recruited

150,000+