Sleep and Circadian Rhythm Study for High Blood Pressure (SCN-BP Trial)

N/A

Waitlist Available

Led By Stephen J Thomas, PhD

Research Sponsored by University of Alabama at Birmingham

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

* Participant in the parent grant (IDH-MEGA)

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up measurements obtained every 30 minutes over 30 hours

Awards & highlights

No Placebo-Only Group

Summary

This trial looks at how sleep and body clock affect nighttime blood pressure.

Who is the study for?

This trial is for participants of the parent grant IDH-MEGA who are interested in understanding how sleep and their body's internal clock affect nighttime blood pressure.

What is being tested?

The study is exploring how sleep patterns and circadian rhythms influence high blood pressure at night using a Constant Routine Protocol to monitor changes.

What are the potential side effects?

Since this trial involves monitoring rather than medication, side effects are minimal but may include discomfort from wearing monitoring equipment or disruption of normal sleep patterns.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ measurements obtained every 30 minutes over 30 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~measurements obtained every 30 minutes over 30 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and measurements obtained every 30 minutes over 30 hours for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in Core body temperature

Change in Melatonin

Secondary study objectives

Change in Blood pressure

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Constant Routine ProtocolExperimental Treatment1 Intervention

Participants complete a 30-hour constant routine protocol to directly examine markers of endogenous circadian rhythms. In a constant routine protocol, participants remain in a dimly lit room (\<10 lux), in a semi-recumbent posture, remain awake, and consume iso-caloric snacks. Saliva samples are collected and core body temperature and blood pressure are measured.

0 / 1Eligibility criteria met