← Back to Search

Sleep Restriction for Insomnia

N/A

Recruiting

Led By Janet M Mullington, PhD

Research Sponsored by Beth Israel Deaconess Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Normal or corrected to normal vision is required

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up one test in a 3-6 day window

Awards & highlights

No Placebo-Only Group

Summary

This trial investigates how lack of sleep affects emotional processing and regulation compared to those with Insomnia Disorder. It will address how distinct neural mechanisms are involved. The findings could help understand the role of sleep in emotional functioning.

Who is the study for?

This trial is for right-handed individuals who can follow the study's rules, avoid alcohol and drugs during the study, and have normal or corrected-to-normal vision. It's not for those using medications affecting sleep or cognition like sleeping pills or antidepressants.

What is being tested?

The study tests how three nights with only four hours of sleep affect emotion processing compared to people with Insomnia Disorder and those with regular sleep. It looks at behavior and brain activity related to emotions when sleep-deprived or diagnosed with insomnia.

What are the potential side effects?

Since this trial involves sleep restriction, participants may experience increased tiredness, mood changes, difficulty concentrating, irritability, and potential stress due to altered sleeping patterns.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My vision is normal or corrected to normal.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ one test in a 3-6 day window

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~one test in a 3-6 day window

This trial's timeline: 3 weeks for screening, Varies for treatment, and one test in a 3-6 day window for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Baseline Emotional Regulation Task with Strategy

Baseline Emotional Regulation Task without Strategy

Reassessment of the Emotional Regulation Task with Strategy Baseline behavioral ratings to emotional stimuli with or without emotion regulation strategies

+1 more

Secondary study objectives

Functional Magnetic Resonance Imaging (fMRI)

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups

Active Control

Group I: Patients with Insomnia DisorderActive Control1 Intervention

Patients with Insomnia Disorder will also be recruited and will be permitted normal nights of polysomnography or actigraphy recorded sleep before participating in an emotion regulation task during functional Magnetic Resonance Imaging (fMRI) scanning

Group II: Normal SleepActive Control1 Intervention

Normal Sleep - Healthy participants are permitted normal nights of polysomnography or actigraphy recorded sleep before participating in an emotion regulation task during functional Magnetic Resonance Imaging (fMRI) scanning

Group III: Sleep RestrictionActive Control1 Intervention

Healthy Participants are sleep restricted to 4 hours of sleep for 3 consecutive days before participating in an emotion regulation task during functional Magnetic Resonance Imaging (fMRI) scanning

0 / 1Eligibility criteria met