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Behavioral Intervention

Cognitive Training for Mental Health Conditions

N/A

Waitlist Available

Research Sponsored by University of California, San Diego

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age 21-55

Diagnosis of mood, anxiety, or traumatic stress disorder

Must not have

Sensory deficits that would preclude completing tasks

Neurodegenerative or neurodevelopmental disorders

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, week 4,week 8, week 16

Summary

This trial will test the effects of a computer-based cognitive training program on individuals with anxiety, depression, or traumatic stress symptoms. Participants will be split into two groups: one receiving the actual training program and

Who is the study for?

This trial is for individuals seeking treatment for anxiety, depression, or traumatic stress symptoms. Participants should be willing to undergo cognitive training and brain response assessments. Specific eligibility criteria are not provided but typically include age range, mental health status, and absence of conditions that could interfere with the study.

What is being tested?

The trial is testing a computer-based cognitive training program called COGENT against a control exercise (Sham Program) thought to be less effective. Participants will be randomly assigned to one of these two groups and their thinking skills and brain responses will be compared before and after the intervention.

What are the potential side effects?

Since this trial involves non-invasive cognitive training programs, side effects may be minimal but can include potential discomfort from sitting at a computer for extended periods or possible frustration if tasks are challenging.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 21 and 55 years old.

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I have been diagnosed with a mood, anxiety, or stress-related disorder.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I do not have sensory deficits that stop me from completing tasks.

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I have a condition that affects the development or function of my brain.

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I have had a serious head injury or another neurological condition.

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I am currently getting support for my mental health.

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I am on psychiatric medication, but not SSRIs.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, week 4,week 8, week 16

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, week 4,week 8, week 16

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, week 4,week 8, week 16 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in cognitive performance

Secondary study objectives

Neuropsychological Performance

Reading Span Blood Oxygen Level Dependent (BOLD) Response

Repetitive Negative Thinking (RNT)

Other study objectives

Anxiety Symptoms

Disability

Mood and Emotions

+4 more

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: COGENT - Cognitive Training Intervention ProgramExperimental Treatment1 Intervention

Computer-administered cognitive training program. COGENT is a modified working memory capacity task designed to train cognitive functioning. COGENT was designed to contain high interference across trials. By requiring repeated practice with utilization of interference control across trials, COGENT is thought to enhance plasticity of cognitive systems and improve performance. That is, training is based on the premise that learning-based neural changes will occur via repeated exposure to a task demanding cognitive control resources

Group II: Non-Training ProgramPlacebo Group1 Intervention

The non-training condition requires participants to complete a similar computer task for the same length of time. The non-training is a modified working memory capacity task designed to be inert. The non-training condition was designed to contain relatively less interference demands across trials.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

COGENT

2021

N/A

~80

0 / 7Eligibility criteria met