~19 spots leftby Apr 2026

New York City Mobile Interventional Stroke Team

(NYC MIST Trial)

Recruiting in Palo Alto (17 mi)
+3 other locations
Overseen byJohanna Fifi, MD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Icahn School of Medicine at Mount Sinai
No Placebo Group

Trial Summary

What is the purpose of this trial?

Endovascular treatment has recently become the recommended therapy for acute stroke after the publication of five randomized trials (MR CLEAN1, ESCAPE2, EXTEND IA3, SWIFT PRIME4, REVASCAT5) in 2015 that demonstrate its efficacy. Hospitals need to adapt to these updated stroke care guidelines, and many hospitals are not appropriately equipped for neurointerventional procedures. Decreased time to treatment is associated with favorable clinical outcomes, and best practices to optimize workflow between comprehensive stroke centers and secondary hospitals have become an important area of study. This prospective study is being conducted on acute stroke cases within the Mount Sinai Health System from 1 June 2016 up until 31 December 2018. The researchers would like to evaluate how variable methods of interventional service delivery for acute stroke affect clinical measures and outcomes. More specifically, the researchers are conducting this study in order to determine whether outcomes of neurointervention for large vessel occlusion in stroke, for patients presenting to and receiving treatment at a comprehensive stroke center, will be superior to that delivered by a mobilized intervention team at a central satellite hospital. In particular, the hypothesis is that factors affecting outcome include presentation to secondary hospital, delays with transfer including traffic conditions and time of day, and the acquisition of complex imaging within secondary hospitals.

Eligibility Criteria

Inclusion Criteria

- all patients who consent to the study and present with acute stroke treated with thrombectomy in the Mount Sinai Health System (Mount Sinai, Mount Sinai West, Mount Sinai Beth Israel, Mount Sinai St. Luke's) from 1 June 2016 - 31 December 2018.

Treatment Details

Interventions

  • Acute Endovascular Stroke Treatment (Procedure)
Participant Groups
3Treatment groups
Experimental Treatment
Group I: Mobilized PatientExperimental Treatment1 Intervention
Group II: Mobilized Neurointervention TeamExperimental Treatment1 Intervention
Patients undergoing endovascular stroke interventions.
Group III: Core Comprehensive Stroke Center TreatmentExperimental Treatment1 Intervention

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Mount Sinai Beth IsraelNew York, NY
Mount Sinai St Luke'sNew York, NY
Mount Sinai Health SystemNew York, NY
Mount Sinai WestNew York, NY
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Who Is Running the Clinical Trial?

Icahn School of Medicine at Mount SinaiLead Sponsor

References