What side effects are associated with this type of intervention?

The Interpersonally Enhanced Recovery and Follow-Up Intervention aims to improve social support and communication skills to aid recovery and prevent future suicidal crises. Common treatments with similar goals include various forms of psychotherapy, such as cognitive-behavioral therapy (CBT) and interpersonal therapy (IPT). These therapies generally have minimal physical side effects but can sometimes lead to emotional discomfort as patients confront challenging issues. Patients may experience temporary increases in anxiety or distress during the initial stages of therapy. However, these effects are typically short-lived and decrease as therapy progresses.

What prior FDA approvals exist?

The FDA has approved several medications for the treatment of conditions associated with suicidal ideation, such as major depressive disorder and bipolar disorder. Notably, esketamine (Spravato) nasal spray has been approved for treatment-resistant depression and has shown rapid reduction in depressive symptoms, including suicidal ideation. Additionally, interventions like Cognitive Behavioral Therapy (CBT) and Interpersonal Psychotherapy (IPT) are widely recognized for their effectiveness in improving social support and communication skills, which are crucial for recovery and prevention of future suicidal crises. These therapies, often used in combination with pharmacotherapy, aim to enhance coping mechanisms and emotional regulation.

What other types of research exist?

Promising novel alternatives for suicide patients in 2024 include: 1) Digital Cognitive Behavioral Therapy (CBT) platforms, which offer accessible and scalable mental health support. 2) Mobile health applications that provide real-time crisis intervention and continuous monitoring. 3) Peer support programs delivered via telehealth, which can offer personalized and empathetic support. 4) Automated telephone continuing care systems that provide regular check-ins and support. 5) Community-based crisis stabilization centers that offer a comfortable and less costly alternative to emergency departments.

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Group and Phone Follow-Up for Emotional Crisis

N/A

Recruiting

Research Sponsored by University of Rochester

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 month after discharge

Awards & highlights

No Placebo-Only Group

Summary

This trial tests a new program called THRIVE for people in suicidal crises at Crisis Stabilization Centers. THRIVE includes group sessions, follow-up calls, and an app to help people feel more connected and less like a burden. The goal is to see if THRIVE helps people start treatment and feel better after leaving the center.

Who is the study for?

This study is for adults experiencing an emotional crisis or suicidal thoughts who are admitted to a Crisis Stabilization Center (CSC). Participants must be able to communicate in English and provide emergency contact information. It's not suitable for individuals under 18, those with acute psychiatric instability like psychosis, or anyone unable to understand the study.

What is being tested?

The trial is testing 'THRIVE', a follow-up care program designed for people after they've had a suicidal crisis. It includes personalized recovery planning and phone check-ins post-discharge from CSCs. The goal is to see if this approach helps people feel better compared to usual safety planning.

What are the potential side effects?

Since THRIVE involves counseling and follow-up rather than medication, there aren't typical side effects like you'd expect with drugs. However, discussing emotional crises can sometimes temporarily increase distress.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 month after discharge

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 month after discharge

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 month after discharge for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Perceived Burdensomeness

Thwarted Belongingness

Treatment Initiation

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: THRIVE + Discharge / Safety PlanningExperimental Treatment1 Intervention

Participants assigned to the intervention condition will receive THRIVE Crisis Recovery and Care Transition Program, which consists of group-based reflections on "giving and belonging" and a plan for community connection and treatment, followed by 3-4 coaching calls to reinforce and troubleshoot the plans.

Group II: Discharge / Safety Planning AloneActive Control1 Intervention

Participants assigned to the control condition will receive Discharge/Safety Planning as it is practiced by Connections Health Solutions per industry best practices.

Do I qualify?Apply below to find out

Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.

Mechanism Of Action

Side Effect Profile

Prior Approvals

Other Research

Common treatments for suicide, such as Cognitive Behavioral Therapy (CBT) and Interpersonal Psychotherapy (IPT), work by modifying negative thought patterns, enhancing problem-solving skills, and improving interpersonal relationships. These therapies are crucial for suicide patients as they help build a supportive network, manage stressors more effectively, and reduce feelings of isolation and hopelessness, which are significant risk factors for suicidal behavior. By improving social support and communication skills, these treatments aim to aid recovery and prevent future suicidal crises.

Looking to the Future: A Synthesis of New Developments and Challenges in Suicide Research and Prevention.Reducing self-harm.