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AI-Powered Eye Exam for Diabetes (ACCESS2 Trial)

N/A
Recruiting
Led By Risa M Wolf, MD
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Meets American Diabetes Association (ADA) criteria for diabetic retinopathy screening: Diagnosis of Type 1 diabetes for ≥3 years, and age 11 or in puberty
Diagnosis of Type 2 diabetes
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights
No Placebo-Only Group

Summary

This trial will test if a nonmydriatic fundus camera, which uses autonomous artificial intelligence software, can increase screening for diabetic retinopathy in underserved youth with diabetes.

Who is the study for?
This trial is for young people with Type 1 diabetes for at least 3 years, aged 11 or older and in puberty, or those diagnosed with Type 2 diabetes. It's aimed at helping underserved youth who haven't had a diabetic eye exam in the past year.
What is being tested?
The study tests if an AI-powered camera can help screen more kids with diabetes for eye problems caused by their condition (diabetic retinopathy) when used during regular care visits.
What are the potential side effects?
Since this intervention involves a non-invasive imaging test using a camera, there are no direct side effects associated with medications or invasive procedures.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have had Type 1 diabetes for 3+ years and am at least 11 years old or in puberty.
Select...
I have been diagnosed with Type 2 diabetes.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Proportion screened for diabetic retinopathy
Secondary study objectives
Diagnostic Accuracy
Percentage of agreement in interpretation of retinal images

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Diabetic Retinopathy Exam at the point of careExperimental Treatment1 Intervention
Participants will undergo a point of care diabetic retinopathy eye exam using autonomous AI. Those that test positive will be referred to Eye Care Provider for dilated eye exam.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Point of Care Autonomous AI diabetic retinopathy exam
2021
N/A
~170

Find a Location

Who is running the clinical trial?

Juvenile Diabetes Research FoundationOTHER
235 Previous Clinical Trials
141,853 Total Patients Enrolled
Johns Hopkins UniversityLead Sponsor
2,339 Previous Clinical Trials
14,881,173 Total Patients Enrolled
National Eye Institute (NEI)NIH
558 Previous Clinical Trials
1,407,971 Total Patients Enrolled
Risa M Wolf, MDPrincipal InvestigatorJohns Hopkins University
1 Previous Clinical Trials
41 Total Patients Enrolled

Media Library

Diabetic Retinopathy Exam at the point of care Clinical Trial Eligibility Overview. Trial Name: NCT05463289 — N/A
Type 2 Diabetes Research Study Groups: Diabetic Retinopathy Exam at the point of care
Type 2 Diabetes Clinical Trial 2023: Diabetic Retinopathy Exam at the point of care Highlights & Side Effects. Trial Name: NCT05463289 — N/A
Diabetic Retinopathy Exam at the point of care 2023 Treatment Timeline for Medical Study. Trial Name: NCT05463289 — N/A
~32 spots leftby Feb 2025