Optical Spectroscopy for Cervical Cancer Detection
Trial Summary
What is the purpose of this trial?
The objective of the work described in this protocol is to determine the optical signatures of cervical dysplasia using optical technologies.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Optical Spectroscopy Bench-Top System for cervical cancer detection?
Research shows that optical spectroscopy, when used alongside colposcopy, has a high sensitivity of 1.00 and a specificity of 0.71 for detecting cervical intraepithelial neoplasia, which are precancerous changes in the cervix. This suggests it can accurately identify cervical changes that may lead to cancer, making it a promising tool for cervical cancer detection.12345
Is optical spectroscopy safe for use in humans?
How does optical spectroscopy differ from other treatments for cervical cancer detection?
Optical spectroscopy is unique because it uses light to detect changes in cervical tissue, offering a non-invasive and potentially low-cost alternative to traditional methods like biopsies. It can be used with or without colposcopy (a procedure to closely examine the cervix), making it suitable for low-resource settings and allowing for automation in diagnosis.134510
Research Team
Nimmi Ramanujam, Ph.D.
Principal Investigator
Duke University
Eligibility Criteria
This trial is for women undergoing colposcopy, LEEP procedures, or follow-up Pap smears for cervical cancer diagnosis and treatment. It's not open to those under 18, anyone unable to consent, or patients with recent bleeding or preterm labor.Inclusion Criteria
Exclusion Criteria
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
Procedure
Participants undergo optical spectroscopy to determine optical signatures of cervical dysplasia
Follow-up
Participants are monitored for safety and effectiveness after the procedure
Treatment Details
Interventions
- Optical Spectroscopy Bench-Top System (Optical Technology)
- Portable Optical Spectrometer (Optical Technology)
- Transvaginal Colposcope (Optical Technology)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Duke University
Lead Sponsor