Brain-Training Exercises for Long COVID

Recruiting in Palo Alto (17 mi)

Overseen byCutter Lindbergh, Ph.D.

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Recruiting

Sponsor: UConn Health

No Placebo Group

Trial Summary

What is the purpose of this trial?

This trial is testing if computerized brain-training exercises can help older adults with Long COVID. The goal is to see if these exercises can improve thinking, mood, and daily activities. The study will check if the exercises are easy to use and if they actually help.

Eligibility Criteria

This trial is for older adults (55+) who've had COVID-19 and are experiencing ongoing cognitive symptoms that started after their illness. They should be fluent in English, have a certain level of cognitive function (TICS ≥ 27), and not planning to change any psychiatric medication doses during the study. People with neurological disorders, prior cognitive impairments unrelated to COVID-19, significant psychiatric conditions, recent substance use disorders, or major sensory/motor issues can't participate.

Inclusion Criteria

I am 55 years old or older.

I have ongoing thinking or memory problems after COVID-19 that other conditions don't explain.

You had COVID-19 in the past, confirmed by a positive laboratory test or a rapid test.

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Exclusion Criteria

History of significant psychiatric illness per DSM-5 criteria that may interfere with study participation or confound results (e.g., schizophrenia or other psychotic disorder, bipolar and related disorders, major depressive disorder with psychotic features, personality disorder)

You have had a problem with alcohol or drugs in the past 2 years.

I do not have major sensory or motor issues that would stop me from participating in the study.

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Treatment Details

Interventions

NeuroFlex (Behavioural Intervention)

Trial OverviewThe trial is testing 'NeuroFlex', which involves computerized brain-training exercises designed as games. The goal is to see if these exercises can help improve thinking, mood, and daily functioning in older adults suffering from Long COVID's lingering effects on cognition.

Participant Groups

1Treatment groups

Experimental Treatment

Group I: Computerized Cognitive RemediationExperimental Treatment1 Intervention