← Back to Search

Alcohol Abstinence + Exercise for High Blood Pressure

N/A

Recruiting

Led By Chueh-Lung Hwang, PhD

Research Sponsored by The University of Texas at Arlington

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through out the study participation (~3 months)

Awards & highlights

No Placebo-Only Group

Summary

This trial will have two phases. In the first, researchers will compare blood pressure, microvascular function, and sympathetic nerve activity in mid-life adults who binge drink with those who abstain or drink moderately. In the second phase, they will examine the effect of 8 weeks of aerobic exercise training on those same measures in the binge drinkers.

Who is the study for?

This trial is for non-smoking men and women aged 50-64 who are postmenopausal, do not use drugs, and have varying alcohol consumption habits. It's not for those with high blood pressure, recent infections, diabetes, heart/liver/kidney disease, obesity or high cholesterol. Regular exercisers and hormone therapy users are also excluded.

What is being tested?

The study investigates how abstaining from alcohol and engaging in an 8-week aerobic exercise program affects blood pressure and vascular function in mid-life adults who binge drink compared to those who don't drink or drink moderately.

What are the potential side effects?

While the trial itself may not directly cause side effects, participants might experience withdrawal symptoms if they're used to heavy drinking. Exercise can lead to muscle soreness or injury if not done properly.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through out the study participation (~3 months)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through out the study participation (~3 months)

This trial's timeline: 3 weeks for screening, Varies for treatment, and through out the study participation (~3 months) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Feasibility of high-intensity interval training

Secondary study objectives

Changes in alcohol intake

Body Weight Changes

Changes in microvascular function

+2 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Group I: Exercise GroupExperimental Treatment2 Interventions

Binge drinkers who have been assigned to exercise group will receive baseline assessment, 8-week exercise training plus alcohol abstinence intervention, and post-intervention assessment.

Group II: Non-exercise GroupActive Control1 Intervention

Binge drinkers who have been assigned to non-exercise group will receive baseline assessment, 8-week alcohol abstinence intervention, and post-intervention assessment.

Group III: Alcohol abstainer/moderate drinker groupActive Control1 Intervention

Alcohol abstainer/moderate drinker will complete baseline assessment only and will not receive any intervention.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Exercise Training

2011

Completed Phase 3

~1470

Do I qualify?Apply below to find out