Amnion-Chorion Membrane for Wound Healing

Recruiting in Palo Alto (17 mi)

Overseen byMuhammad Saleh, BDS, MSD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of Michigan

No Placebo Group

Trial Summary

What is the purpose of this trial?

This study will examine whether adding an amnion-chorion membrane on top of the traditionally used collagen plug will lead to more bone formation compared to the collagen plug only.

Research Team

Muhammad Saleh, BDS, MSD

Principal Investigator

University of Michigan

Eligibility Criteria

This trial is for individuals aged 20-80 needing tooth extraction due to decay, gum disease, fracture, or non-restorable conditions and interested in dental implants. They must have a healthy socket with minimal damage and no infection. Exclusions include liver/kidney issues, uncontrolled diabetes, pregnancy/breastfeeding, blood disorders, active infections or cancer treatments, poor oral hygiene, heavy smokers (10+ cigarettes/day), allergies to study meds like chlorhexidine.

Inclusion Criteria

My surgical wound is not infected and has minimal opening.

I am between 20 and 80 years old.

I need a tooth removed due to decay, gum disease, breakage, or it can't be fixed.

See 1 more

Exclusion Criteria

I have a blood disorder.

Allergies or hypersensitivities to study related medications such as chlorhexidine

Smoke 10 or more cigarettes per day (self-reported)

See 8 more

Treatment Details

Interventions

Socket Preservation (Other)

Trial OverviewThe study tests if adding an amnion-chorion membrane on top of the standard collagen plug used in socket preservation leads to better bone formation after tooth extraction. This could improve outcomes for patients getting dental implants following extractions.

Participant Groups

2Treatment groups

Experimental Treatment

Active Control

Group I: TestExperimental Treatment1 Intervention

Amnion-chorion membrane with collagen plug

Group II: ControlActive Control1 Intervention

Collagen plug