Behavioural Intervention
Hydrogen Water for Chronic Fatigue Syndrome
This trial is studying the potential benefits of a supplement called hydrogen water for people with chronic fatigue syndrome (CFS). The trial will last for 16 weeks and will involve two groups of participants. The
Opioid Antagonist
Low-Dose Naltrexone for Post-COVID Fatigue Syndrome
This trial tests low-dose naltrexone (LDN) to see if it can reduce fatigue and inflammation in people aged 19-69 who have persistent symptoms after recovering from COVID-19. LDN is a small dose of a medication usually used for addiction, which might help by calming the immune system.
Short Chain Fatty Acid
Ca-Mg Butyrate for Gulf War Syndrome
This trial is looking to see if a treatment consisting of butyric acid calcium and magnesium derivatives (Ca-Mg Butyrate) can improve the physical function of Veterans suffering from Gulf War Illness (GWI), as measured by the Short Form Health Survey 36-item (VSF-36). The trial will also focus on the drug's role in restoring gut microbiome and virome, decreasing gastrointestinal disturbances, chronic fatigue, systemic inflammation, and cognitive deficits.
Medical Food
Oxaloacetate for Chronic Fatigue Syndrome
This trial tests a supplement called AEO to help people with ME/CFS who suffer from severe fatigue. AEO supports the body's energy production, which may reduce fatigue. The study will observe the effects of AEO over a period.
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Trials for CFS Patients
Neuroimaging for Chronic Fatigue Syndrome
This trial aims to understand how the brain processes different unpleasant sensations in people with chronic pain conditions like ME/CFS. Participants will undergo three visits where they will experience mild heat and physical exertion tasks while
Procedure
Hyperbaric Oxygen Therapy for Long COVID
This trial is exploring a new treatment for post COVID-19 symptoms, such as fatigue, using hyperbaric oxygen therapy. The findings could help decide if this treatment is feasible for a large-scale research study.
Central Nervous System Stimulant
Solriamfetol for Chronic Fatigue Syndrome
This trial tests if a drug can help treat fatigue for people with chronic fatigue syndrome. Subjects are randomly given the drug or a placebo. Results will determine the drug's effectiveness.
Androgen Replacement Therapy
Testosterone Replacement for Fatigue in Male Cancer Survivors
This trial is testing a testosterone drug to help young male cancer survivors who feel very tired and have low testosterone. The drug aims to increase their energy, improve sexual function, and make them stronger.
Leukocyte Tracking PET/MRI for Multiple Sclerosis
This trial will use PET/MRI to track white blood cells in people with conditions associated with brain inflammation. The hope is that by understanding neuroinflammation better, patients can be better diagnosed and treated in the future.
Trials With No Placebo
Neuroimaging for Chronic Fatigue Syndrome
This trial aims to understand how the brain processes different unpleasant sensations in people with chronic pain conditions like ME/CFS. Participants will undergo three visits where they will experience mild heat and physical exertion tasks while
Procedure
Hyperbaric Oxygen Therapy for Long COVID
This trial is exploring a new treatment for post COVID-19 symptoms, such as fatigue, using hyperbaric oxygen therapy. The findings could help decide if this treatment is feasible for a large-scale research study.
Leukocyte Tracking PET/MRI for Multiple Sclerosis
This trial will use PET/MRI to track white blood cells in people with conditions associated with brain inflammation. The hope is that by understanding neuroinflammation better, patients can be better diagnosed and treated in the future.
PET Radiopharmaceutical
DPA-714 PET/MRI for Chronic Pain and Fatigue
This trial uses a special imaging test to look for brain inflammation in people with chronic pain and fatigue. The test works by highlighting inflamed areas in the brain, helping researchers see if these patients have more brain inflammation compared to healthy individuals.
CAR T-cell Therapy
Cytotoxic T Cells for Lymphoma
This trial is testing whether a new experimental therapy, third party LMP specific cytotoxic T lymphocytes (CTLs), can prevent or treat EBV Disorder including either Hodgkin Lymphoma or non-Hodgkin Lymphoma or Lymphoepithelioma or severe chronic active EBV infection syndrome (SCAEBV) or Leiomyosarcoma which has come back or has not gone away after treatment, including the best treatment.
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Frequently Asked Questions
Introduction to chronic fatigue syndrome
What are the top hospitals conducting chronic fatigue syndrome research?
When it comes to advancing our understanding and treatment of chronic fatigue syndrome (CFS), several hospitals are making significant contributions. In Salt Lake City, the Bateman Horne Center takes a lead role with one active CFS trial and a total of three trials dedicated to this complex condition. Since recording their first trial in 2018, they have been committed to unraveling the mysteries surrounding CFS. Anchorage's Neuroversion is also actively involved in researching CFS, currently conducting one trial and having recorded their initial investigation in 2023. Similarly, Fred Friedberg in Stony Brook has initiated one ongoing trial for CFS after recording its inaugural study in 2022.
In Rochester Hills, the Rochester Center for Behavioral Medicine is making strides as well with an active CFS trial and two previously conducted investigations dating back to 2009. This center recognizes the importance of behavioral approaches alongside medical interventions when addressing this debilitating condition.
On the bustling streets of New york City, Weill Cornell Medicine joins these esteemed institutions by actively engaging in research on CFS through one ongoing clinical trial while also contributing insights from two prior studies commencing initially back in 2018.
The pursuit of knowledge about chronic fatigue syndrome is critical as it affects millions globally yet remains poorly understood. Each hospital plays a crucial role by delving into different aspects of this enigmatic illness—whether through innovative treatments or uncovering underlying mechanisms—to bring hope and relief to those affected by chronic fatigue syndrome worldwide
Which are the best cities for chronic fatigue syndrome clinical trials?
When it comes to chronic fatigue syndrome clinical trials, several cities are at the forefront of research and development. Salt Lake City, Utah and New york, New York each have 2 active trials exploring treatments like Oxaloacetate Arm, Methyl-P plus Nutrient Formula, NAC 3600mg/day, and more. Anchorage, Alaska; Stony Brook, New York; and Rochester Hills, Michigan each have 1 active trial investigating various interventions such as Stellate Ganglion Block, Combined treatment: Heart rhythm biofeedback plus hydrogen water, Solriamfetol and others. These cities offer individuals with chronic fatigue syndrome access to ongoing clinical trials that hold promise for improved understanding and management of this complex condition.
Which are the top treatments for chronic fatigue syndrome being explored in clinical trials?
Ongoing clinical trials are shedding light on the top treatments being explored for chronic fatigue syndrome. One promising approach involves a combined treatment of heart rhythm biofeedback paired with hydrogen water, which is currently being tested in one active trial. Another potential treatment that shows promise is NAC 3600mg/day, also being investigated in one active trial. These novel therapies offer hope for individuals suffering from chronic fatigue syndrome and may provide new avenues for managing this debilitating condition.
What are the most recent clinical trials for chronic fatigue syndrome?
Exciting advancements are being made in the realm of chronic fatigue syndrome, with recent clinical trials offering potential breakthroughs for those affected. One such trial focuses on the use of stellate ganglion block as a treatment option in Phase 1 studies. Additionally, a combined treatment approach involving heart rhythm biofeedback and hydrogen water has shown promise and is currently in Phase 1 testing. Another significant trial explores the efficacy of solriamfetol, which reached Phase 4 trials last year. Finally, testosterone undecanoate and NAC have also undergone clinical investigations to assess their effectiveness for chronic fatigue syndrome patients. These ongoing trials provide hope for improved management and relief from this debilitating condition.
What chronic fatigue syndrome clinical trials were recently completed?
Recently, several clinical trials focusing on chronic fatigue syndrome (CFS) reached completion, demonstrating the medical community's commitment to finding effective treatments for this debilitating condition. These include a trial investigating the use of rituximab as a potential therapy option and another study exploring the effectiveness of cognitive behavioral therapy (CBT). Additionally, researchers conducted a controlled trial examining the effects of graded exercise therapy (GET) in managing CFS symptoms. These trials provide valuable insights into potential treatment approaches for individuals suffering from chronic fatigue syndrome and offer hope for improved quality of life.