Trials in New York, New York
Here are the top 10 medical studies for colorectal cancer in New York, New York
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Phase 3 Trials
Chemotherapy
Vitamin D3 + Chemotherapy + Bevacizumab for Colorectal Cancer
Recruiting2 awardsPhase 3
Birmingham, Alabama
This trial is testing if vitamin D3 along with regular cancer drugs and another drug that helps the immune system can better treat colorectal cancer that has spread. Vitamin D3 may help the body use essential minerals, making the cancer drugs more effective. Vitamin D3 has been shown to slow down cancer cell growth and help them mature, and it has been effective in reducing intestinal tumors in animal studies.
Chemotherapy
ctDNA Testing for Colon Cancer Treatment Prediction
Recruiting1 awardPhase 2 & 3
Pittsburgh, Pennsylvania
This trial tests how well ctDNA testing in the blood predicts treatment for patients with stage IIA colon cancer after surgery. ctDNA are circulating tumor cells that are shed by tumors into the blood. Finding ctDNA in the blood means that there is very likely some small amounts of cancer that remain after surgery. However, this cancer, if detected, cannot be found on other tests usually used to find cancer, as it is too small. Testing for ctDNA levels may help identify patients with colon cancer after surgery who do benefit, and those who do not benefit, from receiving chemotherapy.
Chemotherapy
Nivolumab + Ipilimumab for Colorectal Cancer
Recruiting2 awardsPhase 3
Toronto, Ontario
This trial is testing nivolumab with or without ipilimumab as a treatment for metastatic colorectal cancer in patients with microsatellite instability high or mismatch repair deficiency. The goal is to see if the combination therapy is more effective than nivolumab alone and if either treatment is more effective than chemotherapy.
Kinase Inhibitor
Encorafenib + Cetuximab for Colorectal Cancer
Recruiting2 awardsPhase 3
Pittsburgh, Pennsylvania
This trial is testing a new combination of drugs to treat colorectal cancer that has spread and has a certain type of abnormal gene. The new combination is encorafenib plus cetuximab, which will be taken either alone or with standard chemotherapy.
Alkylating agents
Nivolumab + Chemotherapy for Anal Cancer
Recruiting2 awardsPhase 3
Newark, Delaware
This trial is testing whether adding nivolumab to standard chemotherapy is more effective for patients with metastatic anal cancer. Nivolumab helps the immune system fight cancer, while chemotherapy kills or stops cancer cells from growing. Nivolumab has shown significant effectiveness in treating metastatic squamous cell carcinoma of the anal canal.
Trials With No Placebo
Anti-metabolites
Combination Chemotherapy for Colorectal Cancer
Recruiting1 awardPhase 2
Buffalo, New York
This trial tests a combination of three drugs to treat advanced colorectal cancer. It targets patients whose cancer has spread or cannot be surgically removed. The drugs work together to kill cancer cells, block their growth, and help the immune system fight the cancer. Oxaliplatin is a new drug that has been recently added to initial treatments for advanced colorectal cancer.
Chemotherapy
Vitamin D3 + Chemotherapy + Bevacizumab for Colorectal Cancer
Recruiting2 awardsPhase 3
Birmingham, Alabama
This trial is testing if vitamin D3 along with regular cancer drugs and another drug that helps the immune system can better treat colorectal cancer that has spread. Vitamin D3 may help the body use essential minerals, making the cancer drugs more effective. Vitamin D3 has been shown to slow down cancer cell growth and help them mature, and it has been effective in reducing intestinal tumors in animal studies.
Chemotherapy
ctDNA Testing for Colon Cancer Treatment Prediction
Recruiting1 awardPhase 2 & 3
Pittsburgh, Pennsylvania
This trial tests how well ctDNA testing in the blood predicts treatment for patients with stage IIA colon cancer after surgery. ctDNA are circulating tumor cells that are shed by tumors into the blood. Finding ctDNA in the blood means that there is very likely some small amounts of cancer that remain after surgery. However, this cancer, if detected, cannot be found on other tests usually used to find cancer, as it is too small. Testing for ctDNA levels may help identify patients with colon cancer after surgery who do benefit, and those who do not benefit, from receiving chemotherapy.
Chemotherapy
Nivolumab + Ipilimumab for Colorectal Cancer
Recruiting2 awardsPhase 3
Toronto, Ontario
This trial is testing nivolumab with or without ipilimumab as a treatment for metastatic colorectal cancer in patients with microsatellite instability high or mismatch repair deficiency. The goal is to see if the combination therapy is more effective than nivolumab alone and if either treatment is more effective than chemotherapy.
Alkylating agents
Pulmonary Suffusion for Lung Metastases
Recruiting1 awardPhase 1 & 2
Buffalo, New York
This trial studies a method called pulmonary suffusion, which delivers chemotherapy directly to lung tissues. It targets patients with sarcoma or colorectal cancer that has spread to the lungs. The goal is to kill cancer cells more effectively and reduce side effects by focusing treatment on the lungs.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.