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Trials With No Placebo
Janus Kinase (JAK) Inhibitor
Baricitinib for Oral Lichen Planus
Recruiting1 awardPhase 2
Chapel Hill, North Carolina
This trial is testing baricitinib, a drug that might help people with painful mouth sores from Oral Lichen Planus. It aims to see if the drug can improve their condition and quality of life, and what side effects it might have. Participants will take the drug for several months and visit the clinic regularly for evaluations. Baricitinib has been evaluated for other conditions and has shown potential as a treatment.
Anti-fibrinolytic agent
Tranexamic Acid for Skin Pigmentation Disorders
Recruiting1 awardPhase 2
Detroit, Michigan
This trial is testing tranexamic acid, a medication that can lighten dark patches on the skin, on patients with lichen planus pigmentosus (LPP) and erythema dyschromicum perstans (EDP). These patients have not found consistent relief with other treatments. Tranexamic acid works by reducing inflammation and blocking processes that cause the skin to darken. It is increasingly recognized for its utility in treating various skin conditions, including melasma and post-inflammatory hyperpigmentation.
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.