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What is Briviact
BrivaracetamThe Generic name of this drug
Treatment SummaryBrivaracetam is a medication used to treat partial-onset seizures. It is derived from levetiracetam and binds to the protein SV2A with 20 times more strength. It is available under the brand name Briviact and was approved by the FDA in 2016.
Briviactis the brand name
Briviact Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Briviact
Brivaracetam
2016
7
Effectiveness
How Briviact Affects PatientsBrivaracetam binds strongly to a protein (SV2A) that plays a role in the development of epilepsy by affecting the release of GABA. It is thought that this binding is how brivaracetam helps to prevent epilepsy. Additionally, brivaracetam is thought to also prevent epilepsy by blocking certain sodium channels in the body.
How Briviact works in the bodyWe don't know exactly how brivaracetam prevents seizures.
When to interrupt dosage
The recommended measure of Briviact is contingent upon the identified condition. The quantity of dosage deviates as per the administration strategy specified in the table below.Condition
Dosage
Administration
Seizures
, 25.0 mg, 75.0 mg, 100.0 mg, 10.0 mg, 50.0 mg, 10.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Solution - Oral, Solution, Solution - Intravenous, Intravenous, Tablet, film coated, Tablet, film coated - Oral, Injection, solution, Injection, solution - Intravenous, Injection, suspension, Injection, suspension - Intravenous
Warnings
There are 20 known major drug interactions with Briviact.Common Briviact Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Brivaracetam may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Brivaracetam.
Dosulepin
Major
The metabolism of Dosulepin can be decreased when combined with Brivaracetam.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Brivaracetam.
Ethanol
Major
Brivaracetam may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Briviact Toxicity & Overdose RiskTaking too much of this drug can cause sleepiness and unsteadiness. No evidence that it increases the risk of cancer or affects fertility.
Briviact Novel Uses: Which Conditions Have a Clinical Trial Featuring Briviact?
Two current clinical trials are examining the potential of Briviact to alleviate Seizures.Condition
Clinical Trials
Trial Phases
Seizures
4 Actively Recruiting
Phase 3, Phase 2
Briviact Reviews: What are patients saying about Briviact?
5Patient Review
12/5/2016 I have epilepsy and switched from Keppra to Breviact. I noticed less side effects with this new medication, such as bleeding gums, dry nasal passages and mouth, anxiety, and stuffiness.
4Patient Review
1/28/2019 This medication has been effective for me at treating seizures (have not had any since starting on it), but I have had rough side effects: depression, blurry vision, losing my train of thought mid sentence, mood swings throughout the day, and irritability. I switched to it after having similar side effects while on Keppra, but Keppra wasn't as bad. I am now switching to Lamotrigine hoping that will help.
2.7Patient Review
10/23/2017 Though this treatment is more convenient in that I only have to take two pills per day, it unfortunately has not been as effective at preventing seizures as the Keppra XR brand.
2Patient Review
8/16/2020 I've only been on this for three days and I'm already struggling. The ringing in my ears is so loud that it drowns out every other noise, and it's giving me a headache. I can't stand any more noise.
1Patient Review
12/20/2016 I tried this treatment once before in a trial study at UCSF, and I had visual hallucinations as a result. It's only become legal recently, so I decided to give it another shot; unfortunately, the hallucinations were just as bad as before.
Patient Q&A Section about briviact
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Briviact prescribed for?
"BRIVIACT is a prescription medicine used to treat partial-onset seizures in children 1 month of age or older. Ask your doctor if BRIVIACT might be right for your child."
Answered by AI
Is Briviact the same as Keppra?
"Briviact and Keppra are both anticonvulsant medications that target the synaptic vesicle protein 2A (SV2A) in the brain. Briviact is a newer medication and is more selective for this receptor than Keppra, meaning that it has a higher affinity for the receptor."
Answered by AI
What type of seizures does Briviact treat?
"Briviact is a drug used to treat partial seizures in people with epilepsy. It is for use in adults and children who are at least one month old."
Answered by AI
What are the side effects for Briviact?
"Symptoms of concussion can include: feeling sleepy, dizzy, or tired; feeling nauseous or vomiting; and having problems with balance."
Answered by AI