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What is Natacyn
NatamycinThe Generic name of this drug
Treatment SummaryAmphotericin is an antibiotic used to treat fungal infections. It comes from two types of bacteria found in the soil and is usually applied directly to the affected area. It is commonly used to treat a range of fungal infections.
Natacynis the brand name
Natacyn Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Natacyn
Natamycin
1980
2
Approved as Treatment by the FDA
Natamycin, otherwise known as Natacyn, is approved by the FDA for 3 uses including fungal infections of the cornea and Blepharitis .fungal infections of the cornea
Blepharitis
Conjunctivitis
Effectiveness
How Natacyn Affects PatientsNatamycin is a type of antibiotic that is used to treat fungal eye infections. It is derived from a particular type of bacteria called Streptomyces natalensis and has been found to be effective against a variety of yeast and fungi, including Candida, Aspergillus, Cephalosporium, Fusarium, and Penicillium. When applied directly to the eye, Natamycin is able to reach the corneal stroma, but not the fluid inside the eye. It is only effective against fungi, and will not work against bacteria.
How Natacyn works in the bodyNatamycin works by attaching to a compound in the cell membrane of fungi, called ergosterol. This stops the cells from fusing and changing shape, effectively preventing the fungus from growing. This is different from other polyene antibiotics, which work by changing the permeability of the fungal membrane.
When to interrupt dosage
The advised dose of Natacyn is contingent upon the determined circumstance, including Blepharitis, Conjunctivitis and Fungal Keratitis. The amount of dosage shifts, relative to the technique of delivery (e.g. Suspension / drops or Ophthalmic) displayed in the table below.Condition
Dosage
Administration
fungal infections of the cornea
50.0 mg/mL,
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic
Conjunctivitis
50.0 mg/mL,
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic
Blepharitis
50.0 mg/mL,
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic
Warnings
There are 2 known major drug interactions with Natacyn.Common Natacyn Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Natamycin.
Estetrol
Moderate
The therapeutic efficacy of Estetrol can be decreased when used in combination with Natamycin.
Natacyn Novel Uses: Which Conditions Have a Clinical Trial Featuring Natacyn?
A single trial is presently underway to explore the potential of Natacyn in providing relief from Fungal Keratitis, Blepharitis and Conjunctivitis.Condition
Clinical Trials
Trial Phases
Blepharitis
0 Actively Recruiting
Conjunctivitis
0 Actively Recruiting
fungal infections of the cornea
0 Actively Recruiting
Natacyn Reviews: What are patients saying about Natacyn?
3Patient Review
1/20/2009 It causes pain for about 20 minutes, but it's manageable with pain pills.
1Patient Review
6/23/2010 These drops have been pure torture. They're made up of tiny beads that release the medication, and it feels like sand is constantly in my eyes. I've only been using them for 10 days, but I can't take it anymore. If anyone else has experienced this, please let me know.
Patient Q&A Section about natacyn
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Natacyn used for?
"Natacyn is an eye drop that is used to treat fungal infections of the eye including keratitis (cornea infection), blepharitis (eyelid infection), or conjunctivitis (pink eye)."
Answered by AI
What are the side effects of natamycin?
"You may experience mild irritation or discomfort in your eyes (such as redness, stinging, or burning), an allergic reaction, a change in your vision, chest pain, corneal opacity, shortness of breath, or eye swelling or pain."
Answered by AI
Who manufactures Natacyn?
"The medication Natacyn, which Eyevance acquired from Novartis in 2019, is effective against fungal blepharitis, conjunctivitis, and keratitis caused by organisms including Fusarium solani keratitis."
Answered by AI
How much does Natacyn cost?
"Natacyn is used to treat certain fungal eye infections. It will not work for bacterial or viral eye infections. The average retail price for the most common version of Natacyn is $523.98, but the lowest GoodRx price is $456.23, a 12% discount."
Answered by AI