Suprane
Anesthesia procedures, Induction and Maintenance of General Anesthesia
Treatment
2 FDA approvals
0 Active Studies for Suprane
Treatment for
Anesthesia procedures
What is Suprane
Desflurane
The Generic name of this drug
Treatment Summary
Desflurane, also known as I-653, is an anesthetic gas used during medical procedures. It was developed in the 1980s as an alternative to other inhaled anesthetics, such as methoxyflurane, sevoflurane, enflurane and isoflurane. Desflurane is faster acting and cleared from the body more quickly than these other drugs. It was approved by the FDA in 1992.
Suprane
is the brand name
Suprane Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Suprane
Desflurane
1992
7
Approved as Treatment by the FDA
Desflurane, otherwise known as Suprane, is approved by the FDA for 2 uses including Anesthesia procedures and Induction and Maintenance of General Anesthesia .
Anesthesia procedures
Induction and Maintenance of General Anesthesia
Effectiveness
How Suprane Affects Patients
Desflurane is an anesthetic used to put someone to sleep during surgery. It only works briefly, and is quickly eliminated from the body. However, patients should be aware of possible risks such as malignant hyperthermia, high levels of potassium in the bloodstream, breathing problems in children, changes in heart rhythm, liver or gallbladder issues, harm to the nervous system in children, and post-surgery agitation in kids.
How Suprane works in the body
The way inhalational anesthetics work is not fully understood. They seem to block some nerve signals while boosting others. Desflurane is known to affect certain types of channels and molecules in the body, but the exact way it does this is unknown. One theory suggests that it changes the structure of the protective layer around cells, but this remains unproven.
When to interrupt dosage
The suggested measure of Suprane is dependent upon the diagnosed affliction. The dosage is contingent upon the delivery approach (e.g. Respiratory (inhalation) or Liquid) noted in the table below.
Condition
Dosage
Administration
Anesthesia procedures
, 100.0 %, 2.4 mL/mL, 1500.0 mg/mL
Liquid, Liquid - Respiratory (inhalation), , Respiratory (inhalation)
Induction and Maintenance of General Anesthesia
, 100.0 %, 2.4 mL/mL, 1500.0 mg/mL
Liquid, Liquid - Respiratory (inhalation), , Respiratory (inhalation)
Warnings
Suprane has six contraindications that preclude it from being taken with any of the conditions outlined in the following table.
Suprane Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Liver Dysfunction
Do Not Combine
General Anesthesia
Do Not Combine
Malignant hyperpyrexia due to anesthesia
Do Not Combine
Induction of anesthesia therapy
Do Not Combine
There are 20 known major drug interactions with Suprane.
Common Suprane Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Desflurane may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ephedra sinica root
Major
Desflurane may increase the arrhythmogenic activities of Ephedra sinica root.
Epinephrine
Major
Desflurane may increase the arrhythmogenic activities of Epinephrine.
Ethanol
Major
Desflurane may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Formoterol
Major
Desflurane may increase the arrhythmogenic activities of Formoterol.
Suprane Toxicity & Overdose Risk
Taking too much desflurane can lead to a deeper level of anesthesia, as well as slowed heart rate and breathing. If an overdose happens, the patient may need help with airway, breathing, and circulation. Treatment should include stopping the use of desflurane.
Suprane Novel Uses: Which Conditions Have a Clinical Trial Featuring Suprane?
Zero clinical trials are presently underway to explore the potential of Suprane in Anesthesia procedures.
Condition
Clinical Trials
Trial Phases
Anesthesia procedures
0 Actively Recruiting
Induction and Maintenance of General Anesthesia
0 Actively Recruiting
Patient Q&A Section about suprane
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What is suprane used for?
"SUPRANE can be used as an inhalation agent to maintain anesthesia for both inpatient and outpatient surgery in adults and pediatric patients. After induction of anesthesia with agents other than SUPRANE, and tracheal intubation, SUPRANE can be used to maintain anesthesia in infants and children."
Answered by AI
Is enflurane still used?
"Enflurane is a halogenated ether that was developed by Ross Terrell in 1963. It was first used clinically in 1966 and was increasingly used for inhalational anesthesia during the 1970s and 1980s but is no longer in common use."
Answered by AI
What is desflurane used for?
"Desflurane is a general anesthetic used to cause anesthesia before and during surgery in adults. It is also used as a maintenance anesthesia in adults and children after receiving other anesthetics before and during surgery."
Answered by AI
How is desflurane administered?
"Desflurane is a inhalational anesthesia agent that is administered via the inhalational route. It has a pungent odor, making it difficult to use for the induction of general anesthesia. It is used most commonly for maintaining general anesthesia after induction with an IV or another inhalational agent."
Answered by AI