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Hormone Therapy

Vasopressin, Arginine, ADH for Healthy Subjects (AVP Trial)

Phase 1
Waitlist Available
Led By Richmond Thompson, Ph.D.
Research Sponsored by Bowdoin College
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Healthy men and women 21-30 years of age
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 4 years
Awards & highlights

Summary

This research is being done because we wish to understand how a chemical produced in the brain, vasopressin, effects emotional social communication processes. Understanding how this system works in normal individuals may help us understand why some people, particularly those with autism and/or antisocial personality disorder, have dysfunctional social interactions. This study will test the effects of 3 doses of arginine vasopressin, delivered intranasally, on physiological and behavioral responses to the faces of same- and other-sex individuals in healthy men and women.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~4 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Emotional Responses
Secondary outcome measures
Genetic contributions

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Vasopressin, Arginine, ADHExperimental Treatment1 Intervention
We will test how vasopressin affects emotional responses to facial stimuli in healthy men and women.
Group II: Sterile SalilnePlacebo Group1 Intervention
Sterile saline will be administered intranasally and emotional responses to facial stimuli measured.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Vasopressin
FDA approved

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Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Bowdoin CollegeLead Sponsor
4 Previous Clinical Trials
7,319 Total Patients Enrolled
MaineHealthOTHER
72 Previous Clinical Trials
49,302 Total Patients Enrolled
National Institute of Mental Health (NIMH)NIH
2,820 Previous Clinical Trials
2,692,594 Total Patients Enrolled
~16 spots leftby Jul 2025
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