← Back to Search

Ibuprofen 800 mg for Bone Fractures

Phase 1
Waitlist Available
Research Sponsored by United States Army Research Institute of Environmental Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from pre-exercise to 4 hours post-exercise

Summary

This trial tests common pain relievers on people who do intense jumping exercises to see how these drugs affect bone and muscle health. It focuses on military personnel because they often use these medications. Researchers will measure changes in the body to understand the effects.

Eligible Conditions
  • Bone Fractures
  • Bone Resorption
  • Stress Fractures
  • Osteoporosis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from pre-exercise to 4 hours post-exercise
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from pre-exercise to 4 hours post-exercise for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change from baseline circulating marker of bone formation
Secondary study objectives
Change from baseline circulating marker of bone resorption
Markers of muscle inflammation
Other study objectives
Muscle protein synthesis

Trial Design

4Treatment groups
Experimental Treatment
Placebo Group
Group I: IbuprofenExperimental Treatment1 Intervention
Participants will consume a single dose of ibuprofen prior to a plyometric exercise bout
Group II: FlurbiprofenExperimental Treatment1 Intervention
Participants will consume a single dose of flurbiprofen prior to a plyometric exercise bout
Group III: CelecoxibExperimental Treatment1 Intervention
Participants will consume a single dose of celecoxib prior to a plyometric exercise bout
Group IV: PlaceboPlacebo Group1 Intervention
Participants will consume a single dose of an inert placebo prior to a plyometric exercise bout
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ibuprofen 800 mg
2007
Completed Phase 4
~1030
Celecoxib 200mg
2022
Completed Phase 4
~710
Flurbiprofen 100 mg
2022
Completed Phase 1
~40

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

United States Army Research Institute of Environmental MedicineLead Sponsor
64 Previous Clinical Trials
3,622 Total Patients Enrolled
~3 spots leftby Nov 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top