← Back to Search

Nerve Block for Reducing Pain After Wisdom Tooth Extraction

Phase 2

Recruiting

Led By Gayathri D Subramanian, PhD, DMD

Research Sponsored by Rutgers, The State University of New Jersey

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, post-procedure (day 1) and at post-operative visit (day 8)

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing whether a nerve block can reduce pain for people getting their lower wisdom teeth removed while sedated. People will be asked about their pain and pain meds use for a week after the procedure, and then checked in on 8 days later.

Who is the study for?

This trial is for adults aged 18-64 who need their lower wisdom teeth removed and can consent to the study. They must be healthy enough for sedation, not pregnant, have internet access with a smartphone, and able to take common pain meds like Tylenol or Advil.

What is being tested?

The study tests if a local anesthetic injection called Temporo-masseteric Nerve Block reduces pain after wisdom tooth removal under sedation. Participants will report their pain levels and medication use over the first week post-surgery.

What are the potential side effects?

Potential side effects may include discomfort at the injection site, possible allergic reactions to the anesthetic used in the nerve block, and typical risks associated with dental procedures such as swelling or infection.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, post-procedure (day 1) and at post-operative visit (day 8)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, post-procedure (day 1) and at post-operative visit (day 8)

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, post-procedure (day 1) and at post-operative visit (day 8) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Adverse effects

Masticatory muscle pain to palpation- Temporalis and Masseter

Mean Numerical Pain Rating Scale pain score

+3 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Temporo-masseteric Nerve Block (TMNB) Injection with Local AnestheticExperimental Treatment1 Intervention

Following lower third molar extraction under intravenous sedation, the patient will receive the TMNB local anesthetic nerve block using the standard dental local anesthetic, i.e,. 2% lidocaine with 1:100,000 epinephrine, on the side/s of lower wisdom molar extraction/s

Do I qualify?Apply below to find out