~14 spots leftby Mar 2026

Nonopioid Analgesia After Labral Surgery

Recruiting in Palo Alto (17 mi)
Overseen byToufic R Jildeh, MD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Phase 2 & 3
Recruiting
Sponsor: Henry Ford Health System
No Placebo Group
Prior Safety Data

Trial Summary

What is the purpose of this trial?This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of rotator cuff repair: a treatment group given a nonopioid pain control regimen, and a standard of care control group given standard opioid pain control regimen

Eligibility Criteria

Inclusion Criteria

All adult patients over age 18 and scheduled for a primary or revision labral surgery

Participant Groups

2Treatment groups
Experimental Treatment
Active Control
Group I: Post-Operative Non Opioid Pain ProtocolExperimental Treatment5 Interventions
Patients will be administered a post-operative non-opioid pain protocol consisting of: Celecoxib Ketorolac Gabapentin Acetaminophen Diazepam
Group II: Post-Operative Traditional Pain ProtocolActive Control1 Intervention
Patients will be administered a traditional post-operative pain protocol consisting of: Hydrocodone-acetaminophen 5-325

Acetaminophen is already approved in United States, European Union, Canada, Australia for the following indications:

🇺🇸 Approved in United States as Tylenol for:
  • Pain relief
  • Fever reduction
🇪🇺 Approved in European Union as Paracetamol for:
  • Pain relief
  • Fever reduction
🇨🇦 Approved in Canada as Tylenol for:
  • Pain relief
  • Fever reduction
🇦🇺 Approved in Australia as Panadol for:
  • Pain relief
  • Fever reduction

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Henry Ford Health SystemDetroit, MI
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Who Is Running the Clinical Trial?

Henry Ford Health SystemLead Sponsor

References