← Back to Search

Other

-15 degrees Celsius for 10 seconds for Age-Related Macular Degeneration (COOL-2 Trial)

N/A
Waitlist Available
Led By Arshad Khanani, MD
Research Sponsored by Recens Medical, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up immediately after injection
Awards & highlights

Summary

The purpose of this clinical study is to evaluate the long term safety and efficacy of cooling anesthesia application to the eye as anesthesia for intravitreal injection using a novel cooling anesthesia device.

Eligible Conditions
  • Age-Related Macular Degeneration
  • Diabetic Retinopathy
  • Diabetic Macular Edema
  • Local Anesthesia
  • Intravitreal Injections
  • Macular Edema

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24-48 hours after injection
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24-48 hours after injection for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Incidence of Anesthesia-Related Adverse Events
Pain of Intravitreal Injection: VAS
Secondary study objectives
Pain of Intravitreal Injection (Follow-Up): VAS
Patient Anesthetic Preference
Patient Movement During Intravitreal Injection
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: -15 degrees Celsius for 15 secondsExperimental Treatment1 Intervention
Cooling anesthesia device applied to the eye at -15 degrees Celsius for 15 seconds.
Group II: -15 degrees Celsius for 10 secondsExperimental Treatment1 Intervention
Cooling anesthesia device applied to the eye at -15 degrees Celsius for 10 seconds.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Recens Cooling Anesthesia Device
2019
N/A
~80

Find a Location

Who is running the clinical trial?

Recens Medical, Inc.Lead Sponsor
1 Previous Clinical Trials
40 Total Patients Enrolled
Arshad Khanani, MDPrincipal InvestigatorSierra Eye Associates
5 Previous Clinical Trials
994 Total Patients Enrolled
~12 spots leftby Sep 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top