Nonsteroidal Anti-Inflammatory Drug

Ketorolac for IUD Pain

Hillsborough, NC

Phase 2

Waitlist Available

Led By Amy G Bryant, M.D.

Research Sponsored by University of North Carolina, Chapel Hill

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

18 years or older

Be older than 18 years old

Must not have

IUD placement under sedation or oral anxiolytic

Daily narcotic or NSAID use

Timeline

Screening 3 weeks

Treatment Varies

Follow Up parity is recorded during intake 1 week prior to iud. vas pain scores will be measured during their iud appointment. 5 timepoints will be measured during iud insertion (~10 total minutes), 1 immediately after the procedure, 1 ten minutes afterwards

Summary

This trial aims to see if taking a painkiller, ketorolac, at different times before getting an IUD inserted affects the amount of pain felt during the procedure. This trial is trying

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Who is the study for?

This trial is for individuals who are 18 years or older, can give consent, and want an IUD inserted. It's not for those sedated during IUD placement, replacing an IUD, pregnant, with current infections or certain medical histories like uterine anomalies or allergies to IUD materials.Check my eligibility

What is being tested?

The study tests if taking oral ketorolac (a pain reliever) at different times before getting an IUD affects the pain felt during the procedure. Participants will either receive ketorolac or a placebo without knowing which one they get.See study design

What are the potential side effects?

Ketorolac may cause side effects such as stomach upset, bleeding issues, and allergic reactions in some people. The exact side effects experienced by participants in this trial will be monitored closely.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am 18 years old or older.

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Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I had an IUD placed with sedation or anxiety medication.

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I use painkillers or anti-inflammatory drugs daily.

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I am not pregnant and do not have a genital or pelvic infection.

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I weigh less than 50 kilograms.

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I cannot take ketorolac due to health reasons.

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I have never had an allergy to NSAIDs, liver, kidney, stomach ulcers, or any bleeding in the brain or gut.

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Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ parity is recorded during intake 1 week prior to iud. vas pain scores will be measured during their iud appointment. 5 timepoints will be measured during iud insertion (~10 total minutes), 1 immediately after the procedure, 1 ten minutes afterwards

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~parity is recorded during intake 1 week prior to iud. vas pain scores will be measured during their iud appointment. 5 timepoints will be measured during iud insertion (~10 total minutes), 1 immediately after the procedure, 1 ten minutes afterwards

This trial's timeline: 3 weeks for screening, Varies for treatment, and parity is recorded during intake 1 week prior to iud. vas pain scores will be measured during their iud appointment. 5 timepoints will be measured during iud insertion (~10 total minutes), 1 immediately after the procedure, 1 ten minutes afterwards for reporting.