Flax Muffins for High Cholesterol

Recruiting in Palo Alto (17 mi)

+1 other location

Overseen byHeather J Blewett, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: St. Boniface Hospital

Trial Summary

What is the purpose of this trial?This Clinical Trial is being conducted to study the LDL (bad) cholesterol lowering abilities of flax. The purpose of this study is to find the lowest dose of flax that can lower LDL-cholesterol.

Eligibility Criteria

This trial is for adults with a BMI of 18.5-40 who have high LDL cholesterol levels (2.6-5.0 mmol/L) but no history of cardiovascular disease, diabetes, liver or kidney issues, and aren't on medications affecting blood lipids. They should eat regular meals and not be on weight loss programs or consume excessive alcohol.

Inclusion Criteria

Body mass index 18.5-40.0 kg/m2

Fasting plasma LDL cholesterol 2.6-5.0 mmol/L

Willing to comply with protocol requirements

+3 more

Exclusion Criteria

Other medical, psychiatric, or behavioral factors that, in the judgment of the Principal Investigator, may interfere with study participation or the ability to follow the intervention protocol

I have a history of heart disease or take medication for cholesterol or blood pressure.

Fasting plasma triglycerides ≥ 4.0 mmol/L

+14 more

Participant Groups

The study tests the effectiveness of flax muffins in lowering bad cholesterol (LDL). Participants will receive varying doses of flax to determine the minimum amount needed to reduce LDL levels without other interventions.

3Treatment groups

Experimental Treatment

Placebo Group

Group I: 30g ground flaxseed per dayExperimental Treatment1 Intervention

consume 1 muffin containing 30g ground flaxseed every day for 4 weeks

Group II: 20g ground flaxseed per dayExperimental Treatment1 Intervention

consume 1 muffin containing 20g ground flaxseed every day for 4 weeks

Group III: 0g ground flaxseed per dayPlacebo Group1 Intervention

consume 1 muffin containing 0g ground flaxseed every day for 4 weeks