~54 spots leftby Apr 2026

Long-term Safety and Tolerability of BMS-820836 in the Treatment of Patients With Treatment Resistant Major Depression

Recruiting in Palo Alto (17 mi)
+134 other locations
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Phase 2
Waitlist Available
Sponsor: Bristol-Myers Squibb
No Placebo Group
Prior Safety Data

Trial Summary

What is the purpose of this trial?

The purpose of this study it to evaluate the long-term safety and tolerability of BMS-820836 in patients with depression.

Research Team

BS

Bristol-Myers Squibb

Principal Investigator

Bristol-Myers Squibb

Eligibility Criteria

Inclusion Criteria

Men and women of age 18-65 years (Argentina the minimum age will be 24 years of age)
Patients randomized in parent study who complete CN162-006 and CN162-007 who consent to enter the rollover study.
Patient not randomized in parent study that meet inadequate response criteria

Treatment Details

Interventions

  • BMS-820836 (Antidepressant)
Participant Groups
3Treatment groups
Experimental Treatment
Group I: Arm 3: Placebo + BMS-820836 (2 mg/day)Experimental Treatment2 Interventions
Group II: Arm 2: Placebo + BMS-820836 (1 mg/day)Experimental Treatment2 Interventions
Group III: Arm 1: Placebo + BMS-820836 (0.5 mg/day)Experimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Bristol-Myers Squibb

Lead Sponsor

Trials
2,731
Recruited
4,127,000+
Headquarters
New York City, USA
Known For
Oncology & Cardiovascular
Top Products
Eliquis, Opdivo, Revlimid, Orencia
Christopher Boerner profile image

Christopher Boerner

Bristol-Myers Squibb

Chief Executive Officer since 2023

PhD in Business Administration from the Haas School of Business, University of California, Berkeley; BA in Economics and History from Washington University in St. Louis

Deepak L. Bhatt profile image

Deepak L. Bhatt

Bristol-Myers Squibb

Chief Medical Officer since 2024

MD from Yale University; MSc in Clinical Epidemiology from the University of Pennsylvania