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MuST AKT for Kidney Transplant (MuST AKT Trial)

N/A
Waitlist Available
Led By Dr. Shojai
Research Sponsored by University of Alberta
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
English speaking
No obvious contraindication to kidney transplantation
Must not have
Candidate for multi-organ transplant
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from start date to end date of study recruitment, up to 1 year
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing a new intervention to help patients with kidney failure identify and communicate with potential living donors. The intervention includes support from a multidisciplinary team to educate the patients' social network. The goal is to increase living kidney donations by 34%.

Who is the study for?
This trial is for English-speaking patients with kidney failure who have completed an 'introduction to kidney transplant' module and are eligible for a transplant. It's not for those who've had previous transplants, have high psychosocial risk scores, already identified a donor, can't read basic health-related English or need multiple organ transplants.
What is being tested?
The MuST AKT intervention is being tested to see if it helps patients with kidney failure find living kidney donors by providing personalized support from a multidisciplinary team to educate their social networks about donation.
What are the potential side effects?
Since the intervention involves educational and support services rather than medication, traditional side effects are not applicable. However, participants may experience emotional or psychological stress during the process.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I speak English.
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I am a suitable candidate for a kidney transplant.
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I have completed the kidney transplant introduction module.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I am eligible for a transplant involving multiple organs.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from start date to end date of study recruitment, up to 1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and from start date to end date of study recruitment, up to 1 year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Living Kidney Donor Evaluation Started
Secondary study objectives
Contact Living Donor Services
Identified potential advocates
Living Kidney Donor Evaluation Completed
+1 more
Other study objectives
Advocate and donor attendance at last intervention session
Consent rate
Conversation started
+8 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: InterventionExperimental Treatment1 Intervention
This arm will receive the MuST AKT intervention, which is a multidisciplinary, tailored person-centered behavioural intervention designed to "help and enable" the potential kidney transplant recipients to achieve what is required to receive a living donor kidney transplantation.
Group II: Usual Care (control)Active Control1 Intervention
In the usual care (control) condition, participants will go through the current standard of care, which is a social worker assessment.

Find a Location

Who is running the clinical trial?

University of AlbertaLead Sponsor
939 Previous Clinical Trials
433,875 Total Patients Enrolled
University Hospital FoundationOTHER
7 Previous Clinical Trials
1,729 Total Patients Enrolled
Dr. ShojaiPrincipal InvestigatorUniversity of Alberta
1 Previous Clinical Trials
66 Total Patients Enrolled

Media Library

MuST AKT Clinical Trial Eligibility Overview. Trial Name: NCT04666545 — N/A
MuST AKT 2023 Treatment Timeline for Medical Study. Trial Name: NCT04666545 — N/A
Kidney Transplant Research Study Groups: Intervention, Usual Care (control)
Kidney Transplant Clinical Trial 2023: MuST AKT Highlights & Side Effects. Trial Name: NCT04666545 — N/A
~13 spots leftby Sep 2026