Regional Anesthesia for Knee Replacement Surgery
(TRUE KnORTH 2 Trial)

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 4

Waitlist Available

Sponsor: McMaster University

Prior Safety Data

Trial Summary

What is the purpose of this trial?

To assess feasibility of a a trial investigation postoperative patient-reported quality of recovery after total knee arthroplasty (TKA) with periarticular joint injection (PAI) ± single shot adductor canal block with or without adductor canal catheter infusion.

Eligibility Criteria

This trial is for adults who are about to have their first knee replacement surgery. It's testing different pain management techniques after the operation. People can't join if they don't meet certain health requirements or conditions that the study outlines.

Inclusion Criteria

I am an adult scheduled for my first total knee replacement.

Treatment Details

Interventions

Adductor Canal Block (Procedure)
Adductor Canal Catheter Infusion (Procedure)
Periarticular Joint Injection (Procedure)
Ropivacaine (Local Anesthetic)

Trial OverviewThe study is looking at how well patients recover from knee surgery using two pain relief methods: injections with a drug called Ropivacaine, and normal saline, which is like saltwater. Some will also get an extra numbing technique in the thigh area.

Participant Groups

2Treatment groups

Experimental Treatment

Placebo Group

Group I: cACB activeExperimental Treatment1 Intervention

Periarticular joint injection (medication) + single shot adductor canal block (medication) + adductor canal catheter infusion (medication)

Group II: cACB shamPlacebo Group1 Intervention

Periarticular joint injection (medication) + single shot adductor canal block (medication) + adductor canal catheter infusion (normal saline)