The Potential of a Low Glutamate Diet as a Treatment for Pediatric Epilepsy

Recruiting in Palo Alto (17 mi)

Overseen byKathleen Holton, MPH, PhD

Age: < 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: American University

No Placebo Group

Trial Summary

What is the purpose of this trial?

The study is investigating if following the low glutamate diet for 1 month, as compared to care as usual, can improve seizure frequency, severity, and duration; cognitive functioning; and/or quality of life in children with epilepsy.

Research Team

Kathleen Holton, MPH, PhD

Principal Investigator

American University

Eligibility Criteria

Inclusion Criteria

4 or more seizures per month

Willing to keep all medications constant during the study.

All medications have remained constant for 30 days prior to study enrollment

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Treatment Details

Interventions

Low Glutamate diet (Other)

Participant Groups

2Treatment groups

Experimental Treatment

Active Control

Group I: Low Glutamate dietExperimental Treatment1 Intervention

Participants are put on the low glutamate diet for one month. The low glutamate diet reduces the consumption of free glutamate, while optimizing dietary micronutrient and antioxidant intake.

Group II: Wait-listed controlActive Control1 Intervention

Participants continue care as usual. All all medications must be kept constant during the study period, unless medically necessary.