← Back to Search

Treatment for Air Pollution (SENSE Trial)

N/A
Waitlist Available
Research Sponsored by Environmental Protection Agency (EPA)
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, an average of 1-2 years
Awards & highlights

Summary

The goal of this observational study is to compare the effects of air pollution exposure and nutrition between neighborhoods with high and low social vulnerability scores. The main questions this study aims to answer are: * Does living in a neighborhood with high or low vulnerability influence the response of the heart, lungs, and immune system to air pollution. * Does nutritional status alter the association between air pollution exposure and changes in the heart, lungs, and immune system. Participants (age 25-70 years) that live in neighborhoods ranked high or low on the Social Vulnerability Index (SVI) will take part in 3 visits. Each visit involves the following: * Measurements of heart activity, lung function, and blood to measure changes that may be caused by air pollution. * Questionnaires about the types of food eaten and activities that may modify exposure to air pollution. * Estimation of air pollution exposure using a study iPhone. Participants will carry a study iPhone with them for 24 hours at each visit. The study iPhone runs an application (app) that estimates the amount of air pollution each participant is exposed to. * Wearing silicone wristbands for a week before each study visit. Silicone wristbands absorb air pollutants and are later measured see the types and amounts of chemicals participants are exposed to.

Eligible Conditions
  • Air Pollution
  • Pollution Exposure
  • Healthy Nutrition

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, an average of 1-2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of 1-2 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Heart Rate Variability - HF absolute power
Heart Rate Variability - LF absolute power
Heart Rate Variability - LF/HF power
+3 more
Secondary study objectives
Peripheral Venous Blood - CRP
Peripheral Venous Blood - HDL
Peripheral Venous Blood - IL1B
+13 more
Other study objectives
Concentration of Air Toxics via Silicone Wrist Band

Find a Location

Who is running the clinical trial?

Environmental Protection Agency (EPA)Lead Sponsor
39 Previous Clinical Trials
95,355 Total Patients Enrolled
~43 spots leftby Dec 2025